welcome to the organic green doctor blog

i am a family physician who was diagnosed with
early mild cognitive impairment(mci) amnestic type on december 21, 2010
this is a precursor to alzheimers disease
because of this diagnosis i have opted to stop practicing medicine
this blog will be about my journey with this disease
please feel free to follow me along this path
i will continue blogging on organic gardening, green living,
solar power, rainwater collection, and healthy living
i will blog on these plus other things noted to be interesting

Friday, June 14, 2019

alzheimers news-did this cause our early onset alzheimers disease

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Image result for organicgreendoctor.com joe nash
years ago when i started controlling my highly abnormally elevated ldl cholesterol  i thought it was to prevent early coronary artery disease or stroke
now it seems if this report is true that it was doing more than that

when i was close to 40 i did my first lipid profile
it showed my total cholesterol was well over 300
my triglycerides were well over 500
my hdl cholesterol the good one was below 30
my ldl cholesterol my bad one was well over 200
a level that was known as early heart attack level

now today my total cholesterol is under 200
my trygycerides are less than 100
my hdl is over 40
my ldl is under 100

too late i think
about 40 years too late

it the high ldl cholesterol now after reading this article may also be known as early alzheimers disease level

apoe 4 may represent the cause of 10% of the cases of early onset alzheimers disease
apoe 4 is commonly though called the late onset gene

it seems from their research that the elevated levels of ldl cholesterol also may be one of the causes of early onset alzheimers disease and also late onset alzheimers disease
along of course with other things like smoking obesity lack of exercise poor blood pressure control diabetes etc

i really did not control my ldl choleterol well until after 2000 when i was in my 50s
throughout my 40s looking at my levels they stayed around 150-165
during the early 2000s my levels were much lower thanks to a change in diet exercise and some mild medication
when i was diagnosed with mci that is due to alzheiemers disease i become more aggressive and now with atorvastatin or lipitor i keep it well below 100

so what that means is that i went all my life from birth to my early 50s with an abnormally elevated ldl cholesterol
around my 40s when i first had my ldl cholesterol level done i dropped the number by about 50+ points by changing my diet and my life style

adding to that high ldl was an 8 year of smoking cigarettes and a pipe which didnt help

i have the apoe 4 apoe 4 gene which increases my chance of developing alzheimers disease
the apoe 4 gene is also tied to the elevated ldl cholesterol

my younger brother who died from alzheimers in his early 60s and was diagnosed in his early to mid 50s
so by definition he had early onset alzheimers probably caused by his like mine elevated ldl cholesterol and maybe apoe 4
looking at the dose of his cholesterol meds he took i can predict that his numbers were probably bad like mine were

now he didnt have his apoe 4 gene checked but just knowing that i have the apoe 4 double gene means he had a good chance of having the apoe 4 gene  and most likely he had the apoe 4 double gene also
this means that both my sons have the apoe 4 gene and both his kids have the apoe 4 gene

life style can overcome that apoe 4 gene it seems

these two the ldl cholesterol and apoe 4 gene would explain along with his like me smoking history and blood pressure history as reasons he got diagnosed in his early to mid 50s
i got diagnosed at 60

we both were bad at controlling our cholesterol and diet and blood pressure
from what i can tell i was much better than he was
it looks like not good enough

it seems the apoe 4 like a key fits into the amyloid protein to activate it so that the amyloid accumulates in the brain which is the beginning of this disease probably in both of us began in our late 30s or early 40s

what if
we both had known when we were in for in our 30s what our genetics were and what our ldl cholesterol levels were
what if
we had aggressively both of us attacked the ldl cholesterol with diet and exercise and a strong statin like atorvastatin  lipitor or rosuvastatin crestor
what if
neither of us had smoked

yes what if

its possible had we known we could have both prevented or delayed the onset by years

i hope that this can be a lesson or incentive to our family members especially my sons and my nephews and nieces and hopefully to you to be more vigilant in taking care of your health

it would be nice to be able to visit with my younger brother at our reunion next month or to look forward into my future to know that i would probably be dying of old age
not this terrible disease

yes what if

the organicgreen doctor

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