welcome to the organic green doctor blog

i am a family physician who was diagnosed with
early mild cognitive impairment(mci) amnestic type on december 21, 2010
this is a precursor to alzheimers disease
because of this diagnosis i have opted to stop practicing medicine
this blog will be about my journey with this disease
please feel free to follow me along this path
i will continue blogging on organic gardening, green living,
solar power, rainwater collection, and healthy living
i will blog on these plus other things noted to be interesting

Friday, February 3, 2023

organicgreendoctor: alzheimers news-the superfecta of prevention in mi...

organicgreendoctor: alzheimers news-the superfecta of prevention in mi...: ALZHEIMERS NEWS-THE SUPERFECTA OF PREVENTION IN MIDDLE AGE a superfecta is where you bet 4 horses and the order they win a superfecta in the...

alzheimers news-the superfecta of prevention in middle age

ALZHEIMERS NEWS-THE SUPERFECTA OF PREVENTION IN MIDDLE AGE

a superfecta is where you bet 4 horses and the order they win

a superfecta in the alzheimers world in middle age are
weight
blood pressure
cholesterol
diet

if you bet on these 4 and win there is a good change you can slowdown or prevent alzheimers disease as you get older
that chance may be as much as 50% that you may win
my drug aduhelm which i get at ucla in monthly infusions may only slow down memory loss by 22%
if i had done the superfecta and bet on it when i was 40 my chances of winning the alzheimers race may have been closer to 50% or probably higher

weight
you want your bmi normal
here is  a simple bmi calculator 
just put in your height and weight
eg my weight is 175 and my height is 6 ft giving me a bmi of 23.7
normal is less than 25

not long after my retirement my weight went to 205
my bmi was 27.8
thats overweight
not good

when i was sick 3 years ago my weight went down to 148
my bmi was 20.1
i looked worse than my bmi

obesity causes a thinning of the brain cortex like alzheimers does
plus obese folks tend to have elevated blood pressure and elevated lipids and diabetes
all risk factors for alzheimers disease

except for the last few years i always had a normal bmi

blood pressure
uncontrolled blood pressure in middle age can lead to changes in the brain like alzheimers disease
it also can lead to stroke and vascular dementia as one ages as well as alzheimers disease
it was found that folks in middle age need to keep their blood pressure under 120/80

generally my blood pressure was under controlled but there were times when it was not
back in my middle age years the normal blood pressure was under 140/90
now we know that its 120/80
i probably was around that amount part of my middle age years
i took blood pressure medications not long after i was diagnosed until i lost so much weight 
off meds my blood pressure was normal
recently as i regained my weight my blood pressure has become elevated
i am now back on blood pressure medications
so i have had a good run of 12 years of normal blood pressures

had i known what i know now i would have gotten on blood pressure medications in my 40s

cholesterol
your ldl cholesterol or the bad cholesterol should be under 100
mine never was
my intial ldl level when i turned 40 was around 240
diet changes and exercise brought that down to around 140-160

again knowing what i know now i would have gotten on statins aggressively when i was 40
they werent really around at that time
but a 20 years of taking a dose to make my ldl below 100 probably would have helped me 
my ldl has been below 100 now for 12 years
32 years would have been better

diet
when i turned 40 i altered my diet but it was several years before i got to my almost 90% vegetarian diet
now its closer to a mind diet linked here

i also would add these other things to a healthy lifestyle
exercise
control blood sugar
control stress and treat any anxiety or depression
get adequate sleep
meditate or do meditative activities
keep your brain active
socialize
dont smoke
limit alcohol intake

i firmly believe had at 40 years old i got on cholesterol medication got on blood pressure medication ate the mind diet maintained a normal weight and exercised regularly 
then
i probably would not have been diagnosed with mci at 60
i would have been able to work to 65 or longer
i would have been able to use my medical degree in a volunteer organization after retirement
i would be here longer being mentally intact 

so
if you are middle age
take a good look at your numbers
take your medications to correct them
do all the healthy things you need to be doing
then
the chances are you will be able to enjoy and know you are enjoying your kids graduations your grandkids graduations and maybe your great grandkids graduations

i realize i will probably miss those last two sets of graduations

if i had only knew then what i know now

you though know now

the organicgreen doctor

Thursday, February 2, 2023

organicgreendoctor: there they go again

organicgreendoctor: there they go again: THERE THEY GO AGAIN this is a picture of goleta beach i took 5 years ago  goleta is the town that butts next to santa barbara on the san fra...

there they go again

THERE THEY GO AGAIN

this is a picture of goleta beach i took 5 years ago 
goleta is the town that butts next to santa barbara on the san francisco side
montecito is on the los angeles side of santa barbara

i say goleta is the stepchild of beaches in this area

that building in that picture above is a restaurant that has been renamed and redone
alas this last storm damaged it so it wont get to open on time

that area on the other side of the palm trees is where they dump tons and tons of debris from the floods and mudslides that happen here
why dump it here i ask

you can see the shadow on the beach of the pier that goes out aways out onto the ocean
a lot of folks pier fish from the peer
sometimes the fishing is good if they wouldnt dump junk on the beaches from other sites

at the top of the picture above is the start of the bluffs that ucsb sits on
a beautiful popular university
just below the bluffs is a popular surf site 

dumping all that junk there messes up the beauty of this place

a well known boat captain in this area wrote an article linked here about this beach
he feels like i do about it
he says the county is turning it into a lifeless dump

years and years ago the chumash had encampments here
there was an abundance of fish and wildlife
there was an inlet that allowed some ships to move back and forth from the ocean into a large bay of water
now its just a small size 
the airport here is where part of the bay was
it got all covered with sand and soil to build the airport

so in years years past this was a beautiful site
now every flood and debris flow it gets shut down for months
tons of stuff is dumped here
ruining and contaminating this beautiful quiet beach area
i dont think i would surf out there if i were those students

on that early sunday morning 5 years ago i stood at the end of that long pier 
looking up at the bluffs looking out to sea looking back on the beach
wondering 
why do we ruin this beautiful peaceful site

below are my two blogs i wrote in 2018

_________
2-12-2018

A MUDDY BEACH
i read about this in the online paper
and
saw it on the local news

you know when you hear things
sometimes
you just say
that doesnt seem like the right thing to do

now
i am an outsider here
having lived here for only 7 months
and
not having had gone through this history of mud and fires
around here like folks have who lived here for years

still
i think it gives a different perspective on things
when you are new and fresh to things
you sometimes see things differently

so
it was with me

there it was truckloads of mud slide muck being hauled
down to the beach near here
the goleta beach
to be dumped right on the beach
not just a few truckloads
tons of truckloads stuff

now
granted from what i read
the stuff is trucked an hour or so south
so the debris in there like metal and rocks and logs etc
are removed
then
off to the goleta beach it goes
to be dumped
to be washed apparently over and over again
by the waves coming in on the beach
you know like when you do a sand castle on the beach
and
the tide comes in and eventually washes it away
now i saw this big ole dumpster there on the dumped on beach
that was partially full of all kind of stuff

no the beaches are not white
they are a mud grey color

one of the justifications for doing it here is
the mudslide stuff is destined by nature to eventually end
up in the ocean anyway

now
when we made our long long trip north then around the mountains
to get to los angeles for my last infusion
we passed what seemed like hundreds of dump trucks in a long
long line waiting to dump this stuff into a quarry up north

the goleta beach i think is sort of a poor mans beach
i havent really read that before
its just seems thats the way it is
theres no tourists here

so i wanted to see all this for myself
so one sunday morning before my wife she woke up
i drove over to see for myself

there was all this yellow and red like tape around the dump areas
warning signs were up
dont swim in this water
its contaminated
worse i think with human bacteria
this beach sits in a cove just south of the ucsb campus
you can see the building of the school on the small bluffs close by
i saw several what looked like students walking and biking
on nearby trails
i walked out on the wharf or pier that goes out quite a ways
i would say over a quarter of a mile
there were a lot of folks even this early
as the sun had just popped over the horizon
fishing off the pier

you cant swim here but you can fish here
seems like
not right to me

i looked back over to see the dark spot in the distance
where the dumpster was and big ole heavy machinery was sitting
i guess they all get sunday off

i then walked back to the shore
climbed down off the pier
onto the shoreline
i guess you call it the beach
a dark grey mud colored one

i walked along the edge of the surf as it wiggles back and forth
sometimes catching my feet off guard
getting them all wet
and
i guess
contaminated
i then walked up to the marked off area
the tide was low so i just walked along the waters edge
into and on top of that dark grey mud colored beach
it didnt sink in
it didnt stick heavy to my shoes like mud
but it felt and looked a different consistency
the beach if thats what you call it
didnt feel right as you walked on it
if i took my shoes off
that wouldnt be sand between my toes

i walked up the beach to the machinery
one of those big monster things
you might see in a quarry

i turned and looked back into the sun at the pier
at the beach not affected yet
there was only one other person beside me walking on it
i was the one that broke around the barrier

so after reading about all this
reading about the bacteria counts
reading about how its not chemically contaminated
i dont believe that one
knowing how things work in this world

all i could think
was
why dump that stuff here
i dont understand why

07-11-2018

A MUDDY BEACH REVISITED

5 months ago i wrote this blog a muddy beach about a beach in nearby goleta called the goleta beach
i think it as a poor mans beach
i guess thats why they dumped hundreds of big truckloads of mud and debris and junk and who knows what else in this beach
by digging a deep hole and filling it up so the ocean as the tide would come in and the waves would wash over this what smelled like a cesspool to me
the waves and tide would pull whatever was in that cesspool out into the ocean
the hope was that over time all that stuff would be pulled out to sea and the water around the beach and the beach itself would return to normal

well
it didnt quite worked as planned
why would they dump all that stuff here
i think it was some deal made years ago

this beach has been closed since the first truckload was dumped there
its been closed about 6 months now

if you could look to the left of the above picture
up on a bluff sits the university of california at santa barbara campus
just below the campus and the bluff is a walkway down to the ocean
you can see paddle boaters and surfers and beach activity going on

not far way
just to the right in the below picture
sits that cesspool at goleta beach


ive been there twice
once when i wanted to see for myself what it looked like and smelled like
the second time i brought my wife she with me
we walked out onto the wharf where fishermen were catching fish even though it said no fishing allowed since the water may be poisoned or should i say is poisoned
from there we walked by the cesspool beach
ms b would have said that smells bad  pyoo  wee
from there we wandered up the path around and through the campus to a great lookout over the ocean

this site of the ucsb was once a marine base that was closed
it was shelled by the japanese during ww2 by a sub that surfaced below the cliffs and started shooting away
yes the japanese attacked the mainland during ww2

good thing they werent doing it today they would probably get sick from the water

when you look out over the ocean from there sometimes you see dolphins sometimes whales a lot of kelp beds
way in the distance you can see the menacing oil platforms that caused that disaster that almost destroyed the santa barbara tourist industry

we saw no one swimming at all in the beach area
the smell would be enough to keep you from the water
i did worry about the poor folks that caught fish off the wharf and ate them

all that debris and mud and juices with who knows what from the thomas fires and the montecito mudslides getting dumped there
good for montecito
bad for goleta

now over 6 months later they have decided to reopen the beach
the biggest problem was the bacterial counts wouldnt go down
well lets see 100s of big dump trunk loads of $&!(  just got dumped there
sure that areas contaminated
and
it was and probably still is

the day the reporter that wrote this latest story was there
surprise
there was no one swimming in the water even though it was ok to do so

you know
we arent stupid

i sure hope this area recovers back to where it use to be
its a beautiful location just below the campus
it could be a secret place a lot of folks dont utilize

heres hoping for a full recovery

i still dont understand why they were allowed to dump this stuff on this beach
just down from a campus where 25000 students attend

i thought this was a green environmentally sensitive county and state
a definite black spot on its record
_________

we can do better than this 

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the organicgreen doctor

Wednesday, February 1, 2023

organicgreendoctor: my story revisited #166-when its my time...

organicgreendoctor: my story revisited #166-when its my time...: MY STORY REVISITED #166- WHEN ITS MY TIME... brittany had terminal brain cancer she had part of her brain removed and part of her skull remo...

my story revisited #166-when its my time...

MY STORY REVISITED #166- WHEN ITS MY TIME...

brittany had terminal brain cancer
she had part of her brain removed and part of her skull removed
she was running out of time
she elected to be euthanized making her decision herself
you can google her name to read her story

in the alzheimers movie still alice she had done a plan to euthanize herself when the time came
she had the directions on her computer on how to do it
however
when the time came she was too far advanced
she couldn find the directions on how to do it and couldnt find her medicines she was to use

many of us with terminal diseases like i have think about euthanasia
ive thought about it
i even wrote about it below in my old blog

if my disease progresses like it usually does in alzheimers patients and like it did in my mother and my younger brother 
it will sneak up on you like it did in still alice where you wont be the one to make that decision 
your family will have to make those decisions

without the right paperwork the state may have to make the decision 

i dont want my wife she to have to make that decision or my sons or grandkids
i want to extract all out of this life that i can before i get the point where im done for

then
take away my meds give me water with no ivs or feeding tubes and if i wont eat thats ok
just let me go peacefully

brittany died peacefully with her family around here
she didnt suffer any more and her family didnt either
could she extracted another week another month a few months with them
would she have suffered if she had waited
would they have suffered also

when its time only she knew

when its my time i realize i wont know
i dont want my family to have to make that decision
just make me comfortable like i have written in my living will
know i extended my time here as much as i could

let me go when its time

yesterday i sat in that lounge chair receiving my #26 infusion of aduhelm at ucla
i have about 18 more months of infusions to go in this study
then
ill decide which of the approved antiamyloid drugs do i want to be on
aduhelm or lecanemab or donanemab
or
do i want to get into another clinical trial with eg a new tau antibody drug or another experimental drug to go along with one of these

ill decide in about 18 months which way i want to go

thank goodness for choices
___________
11-05-2014

EUTHANASIA
euthanasia is ending a life intentionally to end pain
and suffering
we all know what it means

many of us have euthanized pets before
in some areas they simply use a gunshot to the head
but most probably use vet assisted euthanasia

and i think we all feel ok with pet euthanasia
its hard but we know the time has come when
the suffering outweighs the living
my wife she has held pets while they slowly
fall asleep
peacefully

like most of us want to go with family and friends
around us


amsj.com

in humans it seems to be more sensitive
i watched the story of brittany maynard closely
before she euthanized herself
or as it called assisted suicide
legal in oregon
but practiced everywhere else but its not ever really
discussed openly
if you are in the medical field and have been around
dying terminal cases you know what i am talking about

have i seen it probably
have i participated probably
after all there are different degrees of this
an elderly person debilitated and severely involved with a terminal
disease like eg alzheimers disease
pneumonia is allowed to progress untreated
food and water is withdrawn
chemo is stopped
all meds are stopped

when i looked at brittany maynard and when i look at cases
like this
i picture her being my daughter my daughter in law my grand
daughter my niece
and then i say
what would i do or want done or what would i say if asked
should she have this done

there is a point of no return in diseases
that when its reached
then its time or its ok to let go or to help

the problem is when is that time
was she there
she thought so
she went out on her own terms

now ive seen these stories about euthanasia in the past
and
seen folks who euthanized themselves
and
to me they did not seem at that point

finding that point that sweet spot
is the essence of all of this
when it becomes a feel good thing the right thing
everyone involved feels ok with it
that may have been with brittanys case

i do think about this a lot
doing euthanasia
and
i have no problem with it personally

since if i have alzheimers disease then i have a terminal
illness that will eventually get to that sweet spot
but
will i be able to know when that time has arrived
will i be able to make that decision
i am afraid thats not the way this disease works
i dont want to go before i have eked out every second
of being with my wife she my sons my daughterinlaws
my future granddaughter
but
when i have maxed out my time here
then
i want to go

i would if i could follow in the footsteps of brittany
and
want my family to feel good about it
feel good about the life i led
ok sorry i fell asleep on yall all the time
but it could have done worse
but
i also dont want to put that burden that decision totally
on them
how to get prepared this far out is difficult
but
i dont want to wait too long
and
i want to be able to be involved
with finding that sweet spot
like finding that perfect sunrise or perfect sunset











for now
the best i can do is a living will with definite things written
like
no ivs
no feeding tube do that to me and i hope you rot in hades
no cpr no ventilation tubes again if you do that to me
i will haunt you for as long as you live
stop all my meds please
and
let me go since i wont be able to make you stop doing those things
to me
or
lets just move to oregon
__________
if i was able when my time comes i would do what brittany did but i realize i wont be able to do that sine i wont be able to mentally make that decision because of the disease progression
i dont want my family to have to make that decision 
just let me go peacefully as best as you can
be at peace at any decision you make

one benefit of knowing what i have so early in the disease is that my wife she and i can have these discussions months to years before the decisions have to be made
most families dont get to do that

a case for early diagnosis

the organicgreen doctor

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Monday, January 30, 2023

organicgreendoctor: why live in a smaller home

organicgreendoctor: why live in a smaller home: WHY LIVE IN A SMALLER HOME this is a picture above of a representative of the condos that are in our complex there are 50 of them the condo ...

why live in a smaller home

WHY LIVE IN A SMALLER HOME

this is a picture above of a representative of the condos that are in our complex
there are 50 of them
the condo complex next to us has another 50
the condo complex a couple of blocks away has another 50
they are at the smallest about 1000 square feet

when we lived at the country n we lived in an approximately 3000 square foot house with a detached garage that was about 400 square feet
our barn was 1200 square feet

yes all that space was filled with stuff

we had 10 acres which 9 acres were left to nature
i planted several trees on those 9 acres of the property and a lot of native grasses
the house sat on 1 acre with a 7 foot fence around it

inside that 1 acre i planted a lot of trees and a lot of native perennials
ok it was 100+ of them
what grass was exposed was mainly whatever was there when we moved in
i also planted several fruit trees

i did all the maintenance on the property doing things like replacing the barn roof rebuilding the garage redoing some of the walls inside the house putting in a 30000 gallon rainwater system

i did all the yard maintenance
i had a 1000 square foot garden of raised beds
we had a large chicken coop with usually around 15 chickens

it took a lot of work to maintain it
all of which i enjoyed doing

today i saw this posting on facebook of a lone small house on a large lot
here is the writing underneath it
thanks to kz

small homes make
wallets fatter
material possessions fewer
relationships stronger
conversations easier
laughing times louder
cleaning times shorter
and 
fun times longer


yep 
i said
thats the things we thought about when we decided to move to santa barbara

we decided to make our move while we were both healthy 
knowing what would happen to me in some unknown time in the future

we notified our kids and family that they needed to come get anything that was theirs or that they wanted
they did and what they didnt want was unloaded

friends and neighbors wanted some of our stuff 
we had a large moving sale and unloaded what was left
then
what was left after that got donated

we left our country n with only our two cars full of what we thought was important
i did bring my 30 yr old multiplying onions and a couple of small malabar  spinach sprouts i had for 15 years in a ziplock bag and a small branch off a cactus plant my wife gave me 30 years ago
all of them are now growing here in santa barbara

it was interesting what we considered important

then
we moved eventually into this 1 bedroom condo that is about 1000 square foot 
we filled with it with good furniture over a period of a few months using the monies from our moving sale

its easy to keep clean
we can talk to each other from one end to the other but we can get privacy for oneself easily
we had to get use to the different noises here
we were use to birds and coyotes and frogs
but
we can walk to our doctor and dental appointments the pharmacy the hospital the grocery store and to restaurants

sometimes we even walk to the downtown area and the farmers market
should we ever need to the bus stop is 1 block away

my wife shes mom lives about a quarter mile away well within walking distance
our grandkids are about 2 miles away and about an hour away

we are about a mile and a half from the beach and a couple of miles to the foothills and mountains

i dont mow grass or water the lawn or trim hedges or do any gardening outside our condo
i do no outside repairs
inside i do some maintenance but leave the electric stuff to a electrician and the more complicated plumbing to the plumber
i use a handy man to do some of the inside repairs that i cant do or dont wont to do anymore

almost everyday i am out the door early to work in my garden plot or i volunteer in our 3 acre community garden doing whatever needs to be done

most of my volunteer work is with the community garden now 
i moved my volunteer hours there during the pandemic since it felt safer

i go to ucla for my infusions once a month 
that trip takes up about 8-10 hours
some months i have to go extra days for mri scans or amyloid pet scans or tau pet scans or memory testing and labs

we usually use those trips to also see our grandkids who leave near ucla

my wife she stays busy grandkidding which she loves to do
she is a known thrifter which she enjoys doing with her mom
she also gets to spend a lot of time with her mom which she has enjoyed since living here

we have not done any trips since the pandemic but we have managed to be busy everyday

we are glad we downsized and prioritized how we are spending our time
we do what we both enjoy doing

sometimes i believe we would all be better off if we all lived in a smaller home

the organicgreen doctor

Friday, January 27, 2023

organicgreendoctor: alzheimers news-why donanemab didnt get approval

organicgreendoctor: alzheimers news-why donanemab didnt get approval: ALZHEIMERS NEWS-WHY DONANEMAB DIDNT GET APPROVAL alzheimers disease starts with amyloid accumulating in the brain the theory is if you remov...

alzheimers news-why donanemab didnt get approval

ALZHEIMERS NEWS-WHY DONANEMAB DIDNT GET APPROVAL

alzheimers disease starts with amyloid accumulating in the brain
the theory is if you remove the amyloid plaques early enough in the disease you can alter the course of the disease

enter the antiamyloid monoclonal antibodies that bind to amyloid or the amyloid plaques and removes it from the brain
hoping doing so will make a difference

there are now 3 monoclonal antiamyloid antibodies in the running for treatment of alzheimers disease
these drugs will not cure alzheimers but it may slow down the symptoms

first is my drug aduhelm or aducanumab
it was approved for use in early alzheimers disease although the approval process was sketchy
the fda approved it but the medicare medicaid folks called cms wont pay for it unless its used in clinical research
they also have required them to do a longer clinical trial to prove if it really works

my study is called the embark study where i have received around 25 monthly infusions of aduhelm or aducanumab after18 months of placebo 
it will report out in 2 years
it  probably will show that it reduces memory decline by about 22% but will have higher aria or microbleeds than the other two
it also is slower in removing the amyloid than the other two

my guess is that my drug aduhelm or aducanumab will not be the one to use even though it does the job

second is leqembi or lecanemab which was just approved by the fda for use in early alzheimers disease
it removes the amyloid faster than aduhelm does
it reduces memory decline by about 27%
slightly more than aduhelm does
it also has the side effect of microbleeds or aria but not as much as aduhelm does
medicare medicaid or cms has not made a determination if they will pay for it
some think it will approve paying for it 
its given as a twice a month infusion

now third is lillys drug donanemab
the fda has decided not to approve it use early until more studies are completed
its expected to give its full approval later this year 

why
donanemab worked too good at removing amyloid
around 100 or so folks were given donanemab but before the full year was up the measurable amyloid seen on amyloid pet scans wqs all gone
so the donanemab was stopped
the fda said they didnt have enough folks complete the year long study
however
later this year they will have enough data to please the fda

it is given as a monthly infusion
its side effect profile is similar to leqembi or lecanemab

seems odd doesnt it that it worked too good so the fda woulnt approve it

its felt the fda will give full approval and that medicare medicaid will likely approve it also
its given as a monthly infusion

so eventually we will have 3 drugs that are antiamyloid monoclonal antibodies to chose from

they all will cost about the same 
a lot of money around $20,000+ a year
about 2-3 months cost to be in a nursing home or memory center

so
right now 
which would i chose to take

probably donanemab
it works better than aduhelm or aducanumab and maybe better than leqembi or lecanemab
the plans are to give it intermittently based on the amyloid load in the brain
lecanemab has to be given every two weeks while the other two are given monthly
aducanumab has worse aria or microbleeds

so
i would probably chose donanemab then leqembi or lecanemab then aduhelm or aducanumab

all 3 of these are doing clinical trials in folks who are prealzheimers or prodromal alzheimers
that means those who have amyloid plaques in the brain on amyloid pet scans but have no memory issues yet
maybe attacking the disease before symptoms start will allow these 3 drugs to be more effective

the fact that i will have 3 drugs to chose from in a couple of years shows we are making progress

the organicgreen doctor

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Thursday, January 26, 2023

organicgreendoctor: my story revisited #165-thanks revisited

organicgreendoctor: my story revisited #165-thanks revisited: MY STORY REVISITED #165-THANKS REVISITED that is me talking for a few minutes at the last walk to end alzheimers in santa barbara yes i crie...

my story revisited #165-thanks revisited

MY STORY REVISITED #165-THANKS REVISITED

that is me talking for a few minutes at the last walk to end alzheimers in santa barbara
yes i cried
the picture below in my old blog is me talking at our family reunion it 2014
i dont remember crying when i was talking but a lot of ny relatives cried that day
it was about a year after my younger brother died in the final stages of alzheimers
he died in a hospice center surrounded by family and friends
thats how i want to go when my time comes

i did get to see him a month before he died
i knew when i left that day i would not ever see him again

this blog below i described what all i was doing to slow down the disease
some of the things i dont do anymore
most are the various supplements i took
i was taking around 17+- a day
some i stopped because of side effects like the ashwaghandha which gave me nightmares
the resveratrol didnt show it helped so i stopped it

there are some new studies coming out about multivitamin use in helping 
if those show it may help i might add a multivitamin to my regimen
until those come out i dont plan on adding those

i also was put on aricept or donepezil early on when i was diagnosed
studies show that my help slow down symptoms 

i really didnt envision that my memory would be intact and in the normal range now 8+ years later

i also had forgotten that i was reinterviewed by the austin american statesman about how i was doing
here is the link to that article
it was a follow up to the larger article done 3 years before also linked here

at the time i wrote this blog below i had not had my amyvid pet scan result
i now have had about 4 or 5
i have lost count
one i got just prior to my starting aduhelm or aducanumab study in 2017 i was told it was positive for amyloid
a requirement to get into the study

when i wrote the blog i was waiting to get into the solanezumab study
i wasnt accepted for one study because my memory test was not normal
the other one i wasnt accepted for i wasnt abnormal enough

looking back i am glad i didnt get into these studies since the results are showing the solanezumab isnt really working

the alzheimers blood test is now here
i have had it for the study i am in
it is used now as a screening tests for these alzheimers clinical trials
soon it will be available in private clinics

one drug for blood pressure that was shown in europe to maybe help was nilvadepene
a med not approved for use in the usa

now its shown that controlling your blood pressure with meds like ace inhibitors like lisinopril and its cousins or arb like valsartan or its cousins helps as well as other blood pressure meds

also controlling your cholesterol with meds like statins eg lipitor or atorvastatin or their cousins help 
as does all those healthy things i listed below

this next week i go in for my #26 infusion of aduhelm or aducanumab at ucla
can you say amyloid be gone
__________

11-03-2014
THANKS

thanks to the hundreds of you who read this article from the
austin american statesman yesterday
doctor keeps alzheimers at bay
and
responded with your kind words

why i may have alzheimers
i had a normal mental status evaluation that changed in 3 years to
being abnormal
i personally noticed those changes
my parents and younger brother had alzheimers disease
i carry the apoe4/apoe4 gene that carries up to a 20x increased risk
of getting alzheimers disease
the levels of beta amyloid and tau protein in my spinal fluid are
abnormal
the pet scan for beta amyloid or amyvid will be done soon

for those who asked
here are the studies i am in

the alzheimers disease neuroimaging initiative or adni study
the largest most important alzheimers study ever done
i get lots of blood drawn neuropsych tests mri scans pet scans for
glucose metabolism pet scans for beta amyloid or amyvid and
spinal taps for beta amyloid and tau protein

a study of the new alzheimers blood test which may be 90%
accurate in predicting if you will get alzheimers disease
it probably will be available in 5 years

then hopefully in december
a study of solanezumab an alzheimers vaccine infusion that may
remove beta amyloid from the brain


first
i am not doing anything different really than thousands
of americans who volunteer to help other folks every day
i know at the habitat builds and the meals on wheels there are
those dedicated folks who are always there doing their part

there are many ways to volunteer
even helping an older neighbor or friend
a disabled one
or
someone temporarily in need

do volunteer
i can speak from experience now after 4 years
the one that benefits the most from volunteering
is that person in the mirror
you

what i am doing to ward off alzheimers disease is not some
secret treatment
its been researched and documented and written about
for years
its mainstream medicine

now one thing to remember is that
in my opinion this doesnt really stop alzheimers disease
once it get rolling
its going to win eventually
but
it slows it down a lot and hopefully makes the symptoms
that you see in people less severe
kinda like
a snowball going down a hill that hits against obstructions
along the way to slow it down
but
eventually it will get to the bottom of the hill
but
it will not be as big

i do think that if a person can start all this preventative stuff
when they are young
even when they are babies and infants and toddlers and
little kiddos and teenagers and young adults
they can maybe prevent themselves from getting alzheimers disease
or
slow it down so much that they will die from something else
when they get real old

eat a heart healthy diet or mediterranean diet
or
if you  are so inclined a gluten free diet sorry i cant do that one
or be a vegetarian or vegan

dont do excesses in your life like eat too much gain weight
drink too much smoke at all use drugs

exercise

get an adequate sleep each day
this one is turning out to be important

control diabetes blood pressure cholesterol

be happy stay mentally active stay socially active

do this and we are talking about a lot of disease prevention
besides alzheimers disease

i have also got a lot of questions about this vitamin and supplement
thing im doing

if you arent going to do this stuff above then dont worry about the
supplement and vitamin thing

i first read the article on the research that was done
here is the full article
then
i discussed this with my primary care doctor and my neurologist
then i had screening labs done looking for problems

i found a low vit d and low b12 which i wasnt expecting
and am taking replacements for them
had my levels not been low i wouldnt have taken those supplements

my homocysteine level was quite elevated
it may be associated with an increased risk of alzheimers disease
its not definitely proven but i as i have said before i dont have
time to wait for it to be proven
so im taking folate  b12 vit b6 each day to lower that number

since i know that i have abnormal levels of beta amyloid in my
spinal fluid and will soon know if my amyloid pet scan is positive
i have elected to take stuff that may lower beta amyloid levels

remember this isnt proven these supplements do this yet
but in animal studies they do

one resveratrol was used in a big study whose results will be out
later this year or next year which will say yes or now if this works
this is the stuff from grapes
it takes tons of grapes to get enough for a daily dose so  thats why
its been put in a pill
if its disproved with this study i will probably stop taking it

some of the supplements i cant tolerate like melatonin
and ashwaganda which may lower beta amyloid and help
some with sleep
i got these god awful disturbing dreams with it

there are 7 things to do that we all should be doing anyway
like those mentioned earlier

so i didnt just start taking this stuff without looking at each
one individually as to whether it fit my circumstance
i look at the side effects and interactions with my medications
like my blood pressure medication or cholesterol medication

if i could access nilvadipine for my blood pressure i would
change to that drug
see last fridays blog

plus
remember there are not many options right now for me
except to do these things
if im wrong this may help then i havent lost much
if im right this may help then ive done myself and my family
some good

please do not just start taking this stuff without looking
at each one closely discussing it with your medical providers
remember these are as much medicines as those prescriptions
you are taking

and also remember this is not a cure for alzheimers disease
its like aricept (donepezil) it slows down the symptoms
but probably doesnt stop the disease

so what do i notice
i feel better
i feel more alert
i have gained more sleep
i dont get leg cramps like i did ( a side effect from the aricept)
i dont feel as tired later in the day
i have less morning nausea

so something is helping in this regimen
im not sure what it is
but its enough i plan to keep on taking it

so again i say
thanks for the interest
dont worry if a cure comes i will be overposting about it
_________
as i sit here i wonder what i will be like in 8 years
i would be 80
i guess if im still writing my blog then that would mean that all that healthy stuff worked and that the aduhelm or aducanumab slowed down the decline some or some other drug that comes along that treats this disease

if on 1-26-2031 i write a blog then ill be happy

the organicgreen doctor