welcome to the organic green doctor blog

i am a family physician who was diagnosed with
early mild cognitive impairment(mci) amnestic type on december 21, 2010
this is a precursor to alzheimers disease
because of this diagnosis i have opted to stop practicing medicine
this blog will be about my journey with this disease
please feel free to follow me along this path
i will continue blogging on organic gardening, green living,
solar power, rainwater collection, and healthy living
i will blog on these plus other things noted to be interesting

Friday, January 21, 2022

organicgreendoctor: alzheimers news-explaining clinical trials

organicgreendoctor: alzheimers news-explaining clinical trials: ALZHEIMERS NEWS-EXPLAINING CLINCIAL TRIALS if you are on a medication or if you have a medical device in your body like an hip replacement o...

alzheimers news-explaining clinical trials


if you are on a medication or if you have a medical device in your body like an hip replacement or knee replacement or heart valve etc then these things have all gone through clinical trials

patients have volunteered to be in these studies which enable them to get care months to years before others can access it

i have been in two clinical trials
one was the adni 2 study where diagnostic testing was evaluated in the diagnosis of alzheimers
the tests were your usual blood tests genetic alzheimers tests ekg mri of the brain amyloid pet scans of the brain various memory tests and neuropsychological tests spinal fluid analysis for amyloid and tau neurological exams
these were done serially over 5 years
this study provided the information thats used now to evaluate folks for memory loss and for testing thats used in all alzheimers drug treatment trials
its the most important alzheimers study ever done

from this study i found out i had mci that was due to alzheimers and that i carry the apoe 4 gene

i am now in biogens embark aduhelm or aducanumab study
its an extension of the phase 3 study of aduhelm for early alzheimers
i have had 14 infusions of aduhelm and 18 infusions of placebo
it will be the study along with a new phase 4 study that will give final proof if aduhelm really works
one year of this drug removes most of the measurable amyloid plaques on amyloid pet scans
i have been able to access this drug months before others will be able to

if it works to slow down this disease then i will have gained time to be with my family and know i was with them

here is a good article on clinical trials that explains what they are and how it works

you can also find clinical trials on any disease or medication at

just type in the disease and or a drug and all the clinical trials for them will show up

most clinical trials are blinded
that means the researcher and the participant doesnt know who is on the real drug or placebo
commonly at the end of the study they let you know if you are on the placebo or not
at the end of my previous aduhelm study they let me know i was on the placebo originally then at 18 months was switched over to the real drug aduhelm or aducanumab

phase 1 is usually on a small number of folks
its looking for safety side effects and dosage

with aduhelm or aducanumab they studied around 100 folks 
at the end of the study they found that those on the higher doses had eliminated most if not all of the amyloid plaque on the amyloid pet scans
placebo patients had no change on scans
memory testing showed some slight improvement on higher dose patients and no change on placebo patients

phase 2 is done on more folks and is used to determine how effective it is

since the aduhelm or aducanumab phase 1 results were so good and alzheimers was such a terrible disease the fda allowed biogen to skip phase 2 studies
a step skip that should not happen
you usually cant rush science

phase 3 is done on an even larger group of folks looking closer at effectiveness and safety and dosage 

this is where the fda and biogen screwed up
the studies werent completed as originally planned
biogen probably tried to influence the fda and researchers and politicians and the alzheimers association to get its approval
it was approved without those 3 phases being doing like they should have been done

thats what has gotten us in this mess with aduhelm or aducanumab being approved before it was adequately studied
we were about 3-5 years away from that point being reached

you cant rush science
you canrt play politics with science
they biogen is paying the price as are also those of us and our families who have this diagnosis

as i said in my interviews something smells about all of this 

phase 4 is commonly required by the fda after a drug is approved to better assess the drugs long term safety and effectiveness

biogen is being required to do a long term phase 4 study on aduhelm or aducanumab that may be somewhere between 5-10 years
if it fails in this phase 4 study it will be removed permanently from the market

should it have been approved
yes with restrictions 
it the approval has opened the door for alzheimers drug treatments coming down the pike that will arrive much sooner now for approval

if it works those few months or years of early approval for those who took it will make it all worthwhile

in summary 
biogen didnt follow the rules the scientific rules 
they and us in the alzheimers world may pay the price

now for me im glad i have access to it 
it gives me hope
there is not another medicine available right now
granted there are others that look promising but they are following the rules and may be years away from approval

so for me and many others aduhelm or aducanumab is the only one available

my guess is that
aduhelm or aducanumab really does work
it definitely no doubt about it removes all the measurable amyloid plaque in the brain after a year of infusions
the question is 
will removing that plaque make a difference
has the train already left the station
the tau tangles and inflammation that occurs after amyloid plaques formed has already started up and is progressing
eg i have had a tau protein pet scan of the brain so researchers know how far down the track it has gone for me
sorry you dont get to see the results
is part of the deal

amyloid accumulates years before tau tangles and inflammation start and longer before memory issues start
if you stop the amyloid from accumulating how long before removing it that it really affects memory decline from getting worse
maybe its 2 years or maybe its 5 years or maybe its 10 years or longer

it may be years before i know what effect aduhelm or aducanumab infusions are having on the progression of this disease

its like damming up a river 
the water keeps on flowing downstream but eventually it slows a lot or stops altogether
thats what im hoping
that aduhelm or aducanumab is like a river dam 

today i go to ucla for my 15th aduhelm or aducanumab infusion 
it will be the second time i have gotten the  high dose of 10 mg/kg of the drug
so far i have had no headache in over two weeks
my last mri two weeks ago was negative for a microbleed or aria
i will have another one in two weeks

do consider a clinical trial for your disease
without folks doing these none of your drugs would be available to you

the organicgreen doctor

Thursday, January 20, 2022

organicgreendoctor: garden news-foodscaping

organicgreendoctor: garden news-foodscaping: GARDEN NEWS-FOODSCAPING when we first moved to the country n i started planting a lot of trees on our 10 acres i even ordered native trees f...

garden news-foodscaping


when we first moved to the country n i started planting a lot of trees on our 10 acres
i even ordered native trees from the forest service
it was cedar and flame sumac that took the best

over time as my native hackberries died which they all do i replaced them with burr oak or mexican white oak or cedar elm or cypress which are mostly native to that part of the country
eventually i had planted enough of these native trees

i also planted a lot of native and xeric perennials like salvia greggi copper canyon daisy lantana jerusalem sage ladybanks rose xemenia etc

i decided that no longer would i plant anything like a tree or a shrub on the property unless we could eat it

that is what foodscaping is 
plant things in your landscape that you can eat

i planted peaches pecans blackberries apples plums grapes lots of herbs like oregano rosemary thyme sage
in fact the flower bed that extended along our large living room was all oregano
we always had oregano
the bees loved the flowers on them when they bloomed
the bees especially loved the rosemary flowrs

thats foodscaping

we added a fig tree near the entry to our back door
you could take a step out the door and pluck a fig for a snack
it also provided shade for our kitchen door

thats foodscaping

on our 50 ft arbor i planted the native grape since it was tough and disease free
mainly the birds ate the grapes but we could have made grape jelly out of it
we mainly let the birds enjoy them
we could have added a better grape but i was satisfied with the tougher native grapes

thats foodscaping

just beyond the arbor i added this keyhole garden using an old 8 ft in diameter water trough

it was kept planted with veggies all year
while we lived there we grew potatoes tomatoes squash onions garlic egg plant lettuce cabbage kale 
you name it we planted that vegetable in it

thats foodscaping

later we added citrus trees in pots 
where we lived you couldnt grow them in the ground since they would freeze
i moved my potted citrus plants into my small greenhouse for the winter
we planted the limes in the picture at the top of this blog
we also grew meyer lemons
these cara cara oranges were grown in our community garden
if you lived in the right environment you could plant a citrus tree in your landscape
its always green
you get to eat its fruit

thats foodscaping
at the country n i didnt really put veggies out in landscape since i used the keyhole bed above
you could put in your landscape beds things like kale or the colorful swiss chard or a pepper plant or two or even a good ole tomato or celery or cilantro or onions or leeks or garlic or broccoli or cabbage or cauliflower
you just tuck them in somewhere 

thats foodscaping

you just want to make sure your landscape is organic and you arent adding poisons to your foodscaping veggies
especially things like weed and feed which wont let your veggies grow and will poison your kids and pets

heck if you dont have a yard you could even do foodscaping in pots on your patio or deck

look around 
i bet you can find a spot for them
enjoy how nice they look and how well they taste

heck you probably are already fertilizing and watering the areas anyway 

you should try foodscaping your yard

the organicgreen doctor

Wednesday, January 19, 2022

organicgreendoctor: my story revisited #120-crs revisited

organicgreendoctor: my story revisited #120-crs revisited: MY STORY REVISITED #120-DRS REVISITED one may ask what is crs its cant remember stuff a common complaint as one aging usually its just norma...

my story revisited #120-crs revisited


one may ask what is crs
its cant remember stuff
a common complaint as one aging
usually its just normal aging

the blog i wrote below in 2014 has the same recommendations that i would make to people today

the big problem is folks dont get evaluated soon enough if there is concern for memory issues by themselves or friends or relatives

this friday i go to ucla for my 15th infusion of aduhelm 
it would be interesting to be able to see  my next amyloid pet scan and my next tau pet scan to see how much has been removed from the brain
my mri of the brain showed no bleeds
i have another mri scheduled next month as part of the protocol of the study
i have no more headaches

thats what people frequently say to me
i cant remember stuff anymore
usually they are grey headed but sometimes they are younger

i tell them
if you occasionally forget an appointment then remember later
if you make occasional errors balancing a checkbook
if you occasionally need help with the settings on a microwave or
recording a television show
if you get confused occasionally about what day it is but figure
it out later
if your visual changes are due to cataracts
if you sometimes have trouble finding the right word
if you make a bad decision occasionally
if you misplace things from time to time then are able to eventually
retrace your steps to find them
if you sometimes feel weary of work family or social obligations
if you develop very specific ways of doing things and become irritable
when a routine is disrupted

you have normal aging behavior

if its more than this i refer them to this link
at the alzheimers association at www.alz.org
that has the 10 early signs of alzheimers

things like repeating questions over and over again
being unable to follow a simple recipe or taking care of monthly bills
driving to a familiar place
forgetting where you are
having trouble judging distance or color contrast
having trouble following a conversation
putting things in unusual places
making poor judgement with money
removing yourself from social activities
easily getting upset outside of your comfort zone

then you may have a problem
again go to the link and read more

then if you or your family think there is a problem take
one of the online quizzes 
the ad8 test at this link
or a family member can go to this link and answer
the 21 question test at this link

then if there seems to be a problem
you should get evaluated

remember there are a lot of treatable causes for memory loss
like b12 deficiency thyroid issues depression high blood pressure etc

when you go to a provider take the online quiz results
and your concerns
usually its good to take a spouse or loved one with you
the provider may want to interview them also

remember dont let the provider ignore your symptoms

get a good history
an exam
probably some labs
a good mental status evaluation like the mmse or mocha test that
is commonly used in the providers office

if indicated a full neuropsychological evaluation
if indicated an mri of the brain

remember the most important test is the history and exam

you are looking for an explanation for your memory loss

if the primary provider doesnt seem interested go to someone
who is interested in memory loss patients
a good source is an alzheimers research center like the one i go to
at ut southwestern medical center in dallas
every state has them
they wont ignore you and will do the workup thats needed

hopefully that answers that question
when someone asks me about crs
in summary not all forgetting is the same
get evaluated if you are worried

the organicgreen doctor

Tuesday, January 18, 2022

organicgreendoctor: covid 19-the whole country just got darker

organicgreendoctor: covid 19-the whole country just got darker: COVID 19-THE WHOLE COUNTRY JUST GOT DARKER the old maps of covid 19 would show some states that were maroon sort of a light maroon color now...

covid 19-the whole country just got darker


the old maps of covid 19 would show some states that were maroon sort of a light maroon color
now with imicron that color has darkened to where to me it looks like black

the wild covid 19 version never got that dark
the delta was darker than the wild or original covid 19
the imicron or like i said a few weeks ago as i called it the oh my cron variant
i was right calling it that
its dark
not the permanent color of our future in the covid world

john hopkins csse and yahoo finance

the cases in the us right now is skyrocketing
in most places it will continue to rise over the next few weeks
ie that black will just get blacker on that map

it is said by infectious disease doctors that all who are unvaxxed will get covid this time unless they are super protected from exposure

if you are triple vaxxxed and have no comorbidity and you catch omicron then you will probably have mild symptoms
as you add comorbidities or risks like age obesity immunosuppressed folks heart disease lung diseases kidney disease etc and if you are triple vaxxxed then your symptoms and how sick you are will get worse 
you are unlikely to die but you may end up hospitalized

if you are double vaxxed your risk of getting a breakthrough infection is increased
you will get sicker than a triple vaxxxed person

if you are single vaxxed you are sort of protected from severe infection maybe

if you are unvaxxed you are in the group that will mostly be hospitalized and die 

i guess it your choice

its our jobs as human beings to protect those in our family and friends that are vulnerable to keep them safe 
as the pope said
getting vaccinated is a moral obligation

i agree

right now the unvaxxed folks are made up of
folks who cant get vaxxed for health reasons
folks who just wont get vaxxed for some reason
kids under 5 who cant get vaxxed yet
hopefully that will happen soon in those under 5 

these folks are the ones that the imicron really wants to infect
next are the vulnerable vaxxed folks

these are the ones above that are providing folks for the virus to infect
a highly highly highly highly contagious virus

it is starting to overwhelm the medical system
remember what these medical facilities are seeing now is only going to get worse
a lot lot lot worse over the next few weeks

grocery stores gas stations pharmacies planes trains are all affected
the whole supply chain is adversely affected

thank goodness in some states like new york where imicron showed up first
the numbers are starting to drop
that will happen elsewhere soon i hope
soon cant get here fast enough

hopefully too many things dont collapse before the next few weeks are up

looking at some foreign countries where the imicron has already peaked
here if we are lucky we will follow the same as these countries

most if not all those unvaxxed will catch imicron
some will get permanently disabled and some will die
the rest will develop some long term immunity to covid
how good it will be probably will wane over the next year

those vaxxed who caught the imicron will also have some immunity to omicron
some of those vaxxed folks with comorbidities may be disabled a few but not many will die

what will be left when this omicron war is over will be
a few folks left with no immunity 
most folks will have some immunity for now

remember the immunity to covid and omicron will fade over time and will need to be replaced

unless of course another variant decides to pop up and sweep the world

i wish to thank those unvaxxed folks who could have gotten vaxxed but refused to do it
putting us where we are today

wherever you live
this omicron will worsen
thats right no matter where you live things are going to get worse a lot worse
if we are all lucky at the end of this surge 
its possible 
things may be a lot lot lot better

i sure hope so
im tired of this 
i know you are too

here is what my wife she and i are doing
avoiding groups of folks
wearing a n95 or equivalent mask
we are not going to travel or attend concerts or sporting events or theaters or indoor events
we both have one comorbidity that is our age
we are both triple vaxxxed

90% of what we usually do 
we still do it
luckily we live in a mild climate and there are easily accessible outside activities 
we have state and local governments that help protect us also
we also are retired and dont have to go into work somewhere

our goal is protect any vulnerable person in our network
mr hudson who hopefully can get vaxxxxed soon

the organicgreen doctor

Friday, January 14, 2022

organicgreendoctor: alzheimers news-we want our money back

organicgreendoctor: alzheimers news-we want our money back: ALZHEIMERS NEWS-WE WANT OUR MONEY BACK aduhelm or aducanumab is a monoclonal antibody that is given intravenously monthly it binds and remov...

alzheimers news-we want our money back


aduhelm or aducanumab is a monoclonal antibody that is given intravenously monthly
it binds and removes amyloid plaques from the brain
removing these plaques leads to a decrease in cognitive decline
a year of these aduhelm infusions remove detectable amyloid on amyloid pet scans

its thought that amyloid plaque accumulation in the brain is what causes alzheimers disease 
its the first thing that happens is this amyloid accumulation
later tau proteins tangles accumulate
then inflammation occurs
all three kill brain cells

the fda gave approval for its use in early alzheimers 
it also is requiring biogen the drug company that makes it to do a phase 4 study to further define how well it works
this study will take several years

i have now had 14 doses of aduhelm in clinical studies
i am in a post fda approval study that will last at least two years
its called the embark study and consists of folks who were in studies prefda approval
its expected my study embark will get extended after two years

i have received about $50,000 of  the drug aduhelm so far
that doesnt include all the labs all the mris all the amyloid pet scans all the ekgs all the memory tests etc that i have to have done
that probably adds another $50,000+ to the cost
so its easily over $100,000 about what a year in a nursing home would cost

a quick aside here
my mri of the brain for microbleeds was negative so i get my infusion again in one week
whew on that one

i did think what i would do if i had to stop these infusions
that would mean i wouldnt qualify for many of the newer treatments for alzheimers disease that are being studied

i would then be like many of you 
left on my own to just do the healthy things folks do to slow down the disease and aricept (donepezil)

aricept only slows done symptoms but doesnt directly treat the disease

as i have written before there will likely not be another drug i can access in a clinical trial since i would not qualify based on strict criteria for entry if you have been previously treated like i have been with an antiamyloid antibody ie aduhelm

so for right now medicare will not pay for the aduhelm infusions
zero is how much they pay
the price of the drug was dropped in half to around $28,000
there will also be charges for physician fees facility fees labs mris maybe an amyloid pet scan or spinal tap and spinal fluid tests ekg etc

right now if you got the money they will give you aduhelm

in march or april medicare will make a final decision on whether they will pay for aduhelm

this week they announced that they plan to only pay for it if it is in a clinical trial
say what i said

what they smoking up there in washington dc

when you are in a clinical trial like i am or in a university etc you dont pay for any of the care you receive
thats zero nada
what the heck are they doing

i guess they mean they will pay the research locale for the aduhelm

thats a big road block to getting the drug

this doesnt really make sense to me

do you know what or get off the pot is what i say 
cover it for those its approved for or dont approve it at all
i dont see this helping much getting the drug to folks 

i agree that more research needs to be done before we really know
it could be years before we know how much this really really works
like with the cholesterol meds like lipitor etc that using it for years decreases the risk for heart disease strokes and probably alzheimers

like with other terminal diseases like cancer etc we in the alzheimers world now dont have time to wait before we know for sure to find out if they really work
we need treatment now
we dont mind taking our chances on experimental drugs

so also this year 
medicare decided it would raise all medicare folks monthly costs by $21.50 to cover the potential cost of aduhelm

say what is what i said
i dont recall this has ever been done before

i could understand an increase because of the cost of covid care
im sure covid costs exceeds what aduhelm would cost
if it was for covid costs i wouldnt mind paying for the increase in medicare

since medicare really isnt going to pay for aduhelm
covering it for research only doesnt help much

all i got to say now is
i want my $21.50 back for the extra money i had to pay for medicare this month

i suggest you call your congress person and tell them the same thing

we want our money back

the organicgreen doctor

Thursday, January 13, 2022

organicgreendoctor: garden news-veggies are on the way

organicgreendoctor: garden news-veggies are on the way: GARDEN NEWS-VEGGIES ON THE WAY that is a zucchini squash that was planted last spring mr hudson picked it this fall  soon in a month we will...

garden news-veggies are on the way


that is a zucchini squash that was planted last spring
mr hudson picked it this fall 
soon in a month we will plant more zucchini squash in the community garden so he maybe can harvest more big squash like this one
we just need to trick him to eat it
he does pull sweet peas off the vine or tomatoes or lettuce and eats them on the spot

we must have about 20 different citrus trees in our orchard
most of it is all donated to food kitchens or shelters or other groups in need of food
here are about 20 containers of various citruses that were harvested recently 

we have over 20 beds that are about 30 feet long that we plant with veggies to donate
these beds are about 3 ft wide
here is a bed before we prep it for planting
that big pile is compost that we made ourselves from shredded veggie plants citrus trimmings tree trimmings etc and from veggie scraps from a nearby food kitchen

this bed was a bed of lettuce that we have harvested over several weeks
all of it has been donated
in this bed we will add this layer of compost plus an organic fertilizer
this will be forked in with a broadfork and raked into a nice 3 ft bed
three driplines will be placed
we have more lettuce growing in our greenhouse that will be planted there soon

those log looking things are banana trees that will be used to edge this bed since it is on a slight slope
this will keep the soil from washing away with the next rains
it also provides a nice border to keep traffic off this bed

this a bed of about 300 leeks we planted last week
if you enlarge this picture you can see the green tops poking from the ground
we buried them about 6 inches so we can get a good long white stalk when its harvested
leeks after a month in the ground can be harvested any time
we usually wait till they get bigger than harvest them gradually over time
that black line is a drip tape with holes every 6 inches that emit about 1/2 gallon an hour
how often we water is determined by how moist the soil is
we use a water meter to measure the soil moisture level
right now the drippers are turned off since we have had so much rain in the last month

this is our row of onions
there are about 300 of them planted an inch deep and 6 inches apart
these are bulb onions called 1015s super sweet and texas early white from dixondale farms
these should be ready for harvest in may or later  

we have about 60 broccoli plants in the garden
this one has been allowed to go to flower
if you look on the bottom middle flower you can see a bee getting pollen nad nectar
you can enlarge the picture to see her at work
worker bees are all female
this head of broccoli was covered with bees
i could hear them when i got close
our hives arent far away so these bees dont have far to travel

this is one of our beds of celery
we have about 60 plus plants
a lot of these will be donated to the organic soup kitchen since they use them in most of their soup recipes

this week we start planting some of our early tomatoes for spring plantings then we will proceed over the next two months to plant all our seeds for our spring garden and also plants for our big veggie spring sale which is a big fundraiser for the garden

this all keeps the volunteers busy 
we are like those bees on our volunteer day
the garden has become a safe place to be in this pandemic since we can work all spread out

if you dont garden yet you should try to garden this year
its good for your soul

we have hired a new garden manager
i am demoted to volunteer assistant garden manager
i look forward to teaching what i know and reaping what i sow 

the organicgreen doctor

Wednesday, January 12, 2022

organicgreendoctor: my story revisited #119-i dont like this gene

organicgreendoctor: my story revisited #119-i dont like this gene: MY STORY REVISITED #119-I DONT LIKE THIS GENE when i see the word gene i think of two things  my friend gene the apoe 4 gene the first one i...

my story revisited #119-i dont like this gene


when i see the word gene i think of two things 
my friend gene
the apoe 4 gene
the first one i like 
the second one i dont like

the first one has the advantage of being a life long friend since medical school
the second one has no advantage at all that i know of

the bad gene puts me at risk for developing alzheimers disease
i have two bad genes the apoe 4 genes not my friend gene that puts me at a more increased risk for developing alzheimers
granted the other gene and i did some things together that probably wasnt good for our health like eating too much bbq and too much crawfish and shrimp and at times too much beer
we missed a lot of sleep during medical school and residency and in our medical practices
the good gene had very little influence on my diagnosis
the bad gene had a big contribution to my diagnosis

the good gene is a friend forever
the bad gene is an enemy forever

the good gene and i are friends and we were both southerners
we were both married with kids
we liked to fish
we liked country music 
in fact he introduced me to willie nelson music

we were opposite though
he was from texas and i was from arkansas
he was an avid longhorn fan and i was an avid arkansas fan
he was the opposite of me on the political leanings
he was opposite of me on religion
he was a pathologist and i was a family physicians
we were opposites in many ways but similar in others

but he was a good gene and is still is

i met the good gene when i was around 28
i met the bad gene when i was 60
i wish i hadnt met the bad gene
im glad i met the good gene

now this bad gene is coming back to be an issue with me
since i now have mci due to alzheimers disease
also the bad gene has put me at a higher risk for having microbleeds in my brain as i get the higher dose of aduhelm 
i receive these infusions monthly in biogens embark aduhelm study 
i have now received the maximum monthly dose 
my last mri over a month ago was normal 

in the last two weeks i started having headaches that lasted over 3 weeks without any explanation except for a possible microbleed or aria from taking aduhelm

i have now been headache free for almost 5 days
yesterday i had a mri of the brain to rule out a microbleed or aria
the mri has to be sent to biogen to read and review to decide if i had a microbleed
that will take about 4 days before i know

if its a microbleed the infusions will be paused until the mri is normal then i would restart the infusions

if there is no microbleed then i go in a week for an antiaduhelm antibody test
if it is ok
then i will resume my infusions in early february at my next scheduled infusion date
i would miss only one infusion

my guess is that i did not have a microbleed and that i will move ahead as scheduled next month

one of my best friends name is gene
one of those forever friends
i could write a lot about him and things we did
but then he would have to write about things i did
then i would write about things he did
well you can see where thats going
nothing good might come of that

im writing about another gene
thats the apoe4 gene and i guess this all could apply to
other genes like eg huntingtons disease

first the apoe4 gene
if you have a double version or
a homozygous version ie the apoe4/apoe4 version
you have an increased chance of developing alzheimers
a 10-30? times chance of developing the disease the late onset
version of alzheimers disease
<6% of us have this combo
up to 25% of you have the singe version of apoe4

so theres a lot of you 25 of 100 of you who read this have
this apoe4 gene
a fairly common gene wouldnt you say

some of you with the apoe4/apoe4 gene will not get alzheimers

so its not one of those 100% genes
like huntingtons disease
like the dominant genes for alzheimers that some get
you get the gene you get the disease
100% guaranteed
(see the colombian alzheimers study)

with eg cystic fibrosis if both parents have a cystic fibrosis gene
then the child has a 25% chance of getting the gene
if the child gets the double gene they have a 100% chance of getting the disease
1 in 30 white folks carry this gene

with the apoe4 gene the double gene apoe4/apoe4 you have a
10-30% chance of maybe getting late onset alzheimers disease

why am i writing about this

i had a lengthy conversation with someone a young someone in
their thirties who got tested you know those things you see on tv
where they swab your cheek and its sent in and then
back comes results that has no real good accompanying explanation
of what that means what it really really means for that particular person

i felt ready when i was tested
i was mentally ready to be tested
i was 60 and had just been told i had mild cognitive impairment amnestic
type that could turn out to be alzheimers disease
based on changes on mental status evaluation over a 3-5 year time period
things i had noticed in my daily life
a strong strong family history of alzheimers disease
so i wanted as much information as possible to help me make decisions
on my personal situation moving forward

i was ready so i was tested
it was though one of those surreal moments when i opened that
letter and read the results
even then i didnt understand what it really all meant like i do now

a positive test with the history above is not a good thing

now move to this person i had the talk with

they have a real strong family history in grandparents and uncles
now i was tested by a real reputable lab that my neurologists used
this person was tested by that lab that advertises on tv that the fda
is trying to shut down

but i dont doubt though that this persons apoe4 test wasnt correct
what was missing was what does it really really mean
the lab where i was tested will not test cause you want it tested
it has to be ordered by someone who feels its necessary and can
appropriately counsel you on what it really really means

so what does this mean for this thirty year old
it means that this person has a 70% chance that this person will not get
alzheimers disease
but im sure this person is locked in on the 30% risk the person was given

the odds are
1 in 1 you will die of something
1 in 7 you will die of heart disease
1in 7 cancer
1 in 28 chronic lower respiratory disease
1 in 108 moving vehicle accident
1 in 340 assault by firearm

1 in 5 is the lifetime risk of developing alzheimers disease in women
1 in 10 for men
(women live much longer than men so they are more likely to get it)

so in summary for this person
i wouldnt have been tested without counseling first
this person could have a 1 in 5 chance of getting alzheimers without the
apoe4 gene
the apoe4/apoe4 gene increases this some
that xx gene a female has increases the chance almost as much as the apoe4 gene

there are so many things that factor in to someone getting this disease
it appears that for the apoe4/apoe4 gene combo it may not be
as important eg as

controlling ones blood pressure
getting exercise
not smoking
having moderate alcohol intake
sleeping normal
controlling anxiety and depression
being happy
staying mentally active
eating a mediterranean diet of less red meat  eat fish fruits nuts veggies
olive oil and whole cereal foods

so be careful of being tested for these different diseases
make sure you are ready if you are going to be tested
make sure you get the appropriate counseling
if you are positive for things like huntingtons or the dominant gene
for alzheimers eg
make sure you have your life planned out
with life insurance disability insurance and maybe long term care insurance
thanks to obamacare health insurance wont be an issue

you wont be able to get any of these after these diagnoses are on
your official medical records
(now in 2022 there are some laws to protect from the insurance companies)
that includes the apoe4/apoe4 gene results

so testing for those gene things should not be taken lightly
do genetic counseling first
the only gene i want to have to be associated with in the future
is my old friend
do put some thought before you get genetic testing for diseases
make sure you understand what it means if the test is positive

ill take the good gene anytime

the organicgreen doctor