dear ms b-you are my hero

DEAR MS B-YOU ARE MY HERO

we have a good friend that would definitely not like this picture
she would probably say what awful grandparents you are
letting ms b hold that snake

im sure she wont be able to sleep tonight thinking about that snake
this friend is the one we gave a christmas present one time
a snake aquarium cage wrapped for christmas
inside was a realistic fake snake
the kind if you didnt know it wasnt real and if you had this fear of snakes .........well you can just imagine the scene that christmas evening at the present opening event
we even have it on video

now one of the things that i want in dealing with you ms b
is for you to have a love of  nature and not fear it
like
spiders
bees
rolly pollys
worms

now
add snakes to that list

this picture was from the local museum one day last week when your
other not my wife she grandmother brought you for a tour of the museum
i wonder if thats her grandmother handing you that snake
i know for sure it wasnt my wife she
guarantee it

was i ever a proud granddaddy to see you holding that snake
slithering around in your hands and arms

of course i recognized that snake
a rosy boa
i use to have one myself
in fact i had it when my wife she and i were dating
its the one that had to disappear when we got married
my wife she tolerated it before we got married
but
didnt tolerate it afterwards

we guys know how that works
it did

i have no fear of snakes but i do respect them
having gone out rattlesnake catching while in college

several times at the country n i would use my homemade snake catcher to snatch a slithering rattlesnake that appeared on our property replacing it over my property fencing as a donation to my neighbors
dont worry they had a hundred acres with nothing but nature on it
i never let my wife she know when i did that

another time a large big ole rat snake sat on the top of our water tank sunning himself looking down on my wife she as she soaked in the hot tub butted up against that tank
i never let her know about that one either

ms b sometimes in a marriage you have to keep things to yourself
its best if you do that

now this rosy boa makes a great pet for kids and grandmothers
they are friendly and easy to play with

as i look around our condo i have located a few sites that an aquarium
for snakes could easily fit
then ms b when you come over
well you could take your rosy boa out and play with it
with my wife she not being home of course
and
we dont have to tell anyone
it will be our secret

i guess ill have to check those hoa regulations to see if snake pets
are allowed

ms b
im glad you were exposed to snakes and will develop no fear of them

next on the list
is spiders

ms b most spiders are the good guys
i rarely ever remove one if i see one
especially in my garden

maybe ill catch one for you to hold
like you did that rosy boa

yep
you are reaching hero status with me

the organicgreen doctor

dont worry be happy

DONT WORRY BE HAPPY

amazon.com

thats my new motto
it seems the millennials are having problems with this one

when this course was offered at yale 1/4 of the student body signed up for the class called the happy class
they had to move it to large auditoriums to accommodate the large numbers

it will eventually have to be eliminated though since its sucking away so many students from other classes its interfering with other departments success

now most yale graduates dont have to be too worried about getting a job
since
most are able to do so when they graduate

near where we live is a popular coffee place where when you walk by its always busy
if its open its busy
when you go inside or sit outside you see a lot of folks visiting
all of course half the time looking down at their electronics
half listening it seems

then
there are a lot of folks just sitting there alone
looking at their laptops or phones or tablets
i always wonder what they are doing
what they need to be doing is day dreaming
or
interacting with other folks

the professor who teaches this popular class talks about how personal interaction is gradually being eliminated from our society

i was at a large store the other day and as i went to check out
there were only self check out lines with 1 person to help to cover a large volume of checkouts
that interaction with the grocery clerk or retail clerk is all gone or going away it seems

when i lived in texas i shopped at heb for groceries
i had my favorite check out folks
we always struck up conversations with each other
talking about the weather or some item i bought or their grandkids or if they were a student what their plans were

here i like going to trader joes since its always fun to interact with the clerk
they must train them all to be friendly and converstational
i feel good every time i check out there
i notice they have no self check out lines
they trader joes seem to understand thats what we all want
and
need
social interaction

we can order what we want online
especially with amazons efficiency
why buy something you have to drive and park to buy it
when
you can sit at home with your coffee 24/7 and buy what you want and it will appear on your doorstep in two days at the same price as going to the store

you can order from most restaurants here now
uber will pick it up
deliver it to your front door

you dont have to make a reservation or stand in line or ask for more water or put up with a noisy table next to yours or have to wait for the food or have to wait for the check etc
it makes life easier
but
does it make life better
does it make life happier

those interactions may be important to all of us
since
we all are starting to isolate ourselves more and more

for the millennials and the students they are even worse at isolating themselves
you can order stuff online talk online or text online or take classes online
but
doing that offline learning how to interact with others
may make your life better
make your life happier

my concern is this will all get worse
not better

those yale students and other students and millennials and well probably all of us
we want more
we want to make our life better
we want to make our life happier

they the yale students learn how to change things up to make their life happier and better

we all probably could learn from this class or one like it

it makes me look at my life
making sure i and my wife she have a lot of interactions with folks
to not become millenialized

our family interactions especially ms b
our volunteering
our walking to the grocery store and pharmacy and restaurants and doctors office and dentist office and relatives all force interactions on us that driving or staying at home wouldnt allow us to experience

so
my our new motto is like the name of that yale course
the one the students are trying to learn before they enter the world on their own

dont worry be happy

the organicgreen doctor

alzheimers news-its not my drug

ALZHEIMERS NEWS-ITS NOT MY DRUG

several folks contacted me yesterday asking if the drug that was in the news was my drug
it was on a lot of tv channels and on my newsfeeds yesterday and today

that drug is called ban2401
my drug is called aducanumab
both are made by biogen


ban2401 attacks the amyloid at a particular site called protofibrils
aducanumab attacks the amyloid at a different site
both drugs grabs the amyloid and removes it
both are antibodies against the amyloid given as an injection or an infusion

ban2401 is about 2-5 years behind my drug aducanumab
ban2401 is in phase 2 studies
aducanumab is in phase 3 studies

the aducanumab phase 3 study ends for me after my next 2 infusions in 6 weeks
others in my study are further behind me
there are about 1200+ of us in the aducanumab study

it should be all finished in 2019 with the final results out probably 2020
it could be on the market the following year or two pending fda approval
ban2401 wont be available if it continues to do well until 2021+

dont worry starting in october i begin to definitely receive the aducanumab and not the placebo and will receive it for another 18 months or longer
that should carry me into 2020 when the results come out
if it doesnt work then ill stop it
if it does work then ill probably stay on it since they usually will continue the studies for a long term after that
ie
im covered for now

ban2401 in this phase 2 study didnt work except at the higher doses
it worked best in folks like me with the apoe 4 gene
this higher dose study has only about 200-300 folks in it
the drug in the higher dose not only removed the amyloid
but
the patients memory improved by 30% on the memory tests they used


aducanumab results from nature

my drug aducanumab in its phase 1 study on 100+ patients also worked best at the higher doses
the amyloid was mostly removed
the higher the dose the more removed
also all in the phase 1 study had improvement in their memories
except
those who received the placebo
it always sucks to be in the placebo group

so unlike the ban2401 drug it worked at the lower doses just not as strongly
the folks in the phase 1 study of aducanumab have now been followed for over 5 years
they have continued to have less amyloid in the brain and have showed continued improvement in their memory

my aducanumab drug also has higher side effects at the higher doses
in fact in the phase 3 study they dropped the highest dose because of the side effects
the biggest side effect is micorobleeds that may occur as the amyloid plaques are removed
a side effect that most of us with this disease would readily accept
but
the fda doesnt like them

when my drug aducanumab publishes its results next year or next expect the same hype that the ban2401 is getting now
the difference is that it will be available first for treatment for alzheimers disease

it probably will be used in folks with prealzheimers disease
prealzheimers disease is where many of you are
you dont have symptoms but your amyloid pet scans and or your spinal fluid for amyloid are positive
you just dont know that yet

it will be also used in folks like me with the diagnosis of mild cognitive impairment or those with mild alzheimers
it probably wont be used in moderate to severe alzheimers since by then so much damage has been done that little gain will come from using this expensive drug on those patients

getting diagnosed early is going to be important in the near future if you are going to be able to stop or slow down this disease

in the meantime be aggressive in taking care of your health

the early the better is the rule

so thats my answer to the question
is this your drug

the organicgreen doctor