welcome to the organic green doctor blog

i am a family physician who was diagnosed with
early mild cognitive impairment(mci) amnestic type on december 21, 2010
this is a precursor to alzheimers disease
because of this diagnosis i have opted to stop practicing medicine
this blog will be about my journey with this disease
please feel free to follow me along this path
i will continue blogging on organic gardening, green living,
solar power, rainwater collection, and healthy living
i will blog on these plus other things noted to be interesting

Friday, October 21, 2016

alzheimers news-it works on mice


yesterday i stood and answered questions from several folks
for about an hour and a half
this is the favorite presentation that i do
no slides
no handouts
no board to write on
me standing up there
telling briefly my story
getting the folks in the audience to ask me questions

i am surprised that folks arent aware more of
what causes alzheimers disease
what you can do to prevent or slow it down in your family
what exciting research is out there
that may bring us that treatment drug

usually at these events there is usually a lot of wet eyes
as they talk or ask questions about alzheimers
and their loved ones

there just needs to be an education class
for folks when their family member gets diagnosed
you know like
when you get diagnosed with diabetes
you go to all those classes
explaining diabetes
esplaining what to eat how to exercise etc

well so should that be with alzheimers
an education class for alzheimers

ill start one

usually in the audience there is always at least one person
usually there are more
that is or is becoming an
isolated caregiver
looking sort of overwhelmed

there was one yesterday
she was linked up with caregiver groups
she was linked with the research center where i go
her husband probably qualifies for the study i am
trying to get into

like my wife she says
education is a good thing

so we need it for alzheimers

i saw an article recently on this
can a cancer drug reverse parkinsons and dementia

Image result for nilotinib
there is a cancer drug that is used for leukemia
its approved by the fda already for it use

researchers at georgetown university gave it to mice who had alzheimers
yes mice get alzheimers
they the scientists put the alzheimers gene in the mices brains
it makes beta amyloid which accumulates
they all get alzheimers disease

the drug works by turning on the garbage cells in the brain
to clean up any rogue proteins in the brain
like beta amyloid thought to be the culprit in alzheimers disease

the study i am trying to get in with the adu drug
was given to these mice
the beta amyloid a lot of it got cleared from the brain
the mice got better
next step
it seemed to work in those first studied
next step
hopefully me

so these mice studies are important
the cancer drug is called

when given to parkinson patients they got better

now the georgetown researchers plan to give it to alzheimers patients
in a study

if it really works its already available legally
all will need to happen is to have a doctor order it

maybe hopefully it will work
im game

the organicgreen doctor

Thursday, October 20, 2016

country n news-eat what you sow


thats what we do around here
in our country n garden
here is a dish of veggies that i grilled this last week
no i didnt got to the grocery store to buy them
there are no prepackaged treated veggies in here

all of these ingredients
all organically grown
sure to be chemical free
most just pulled from the country n garden
well except for the green beans onions garlic
the green beans were frozen from this springs harvest
all fresh ingredients
farm to fork meal

olive oil
ms dash original seasoning blend
some crushed pepper

Image result for organicgreendoctor.com onion chimes
onions from this springs garden
i have them in the onion chimes hanging in our garage

bell peppers i planted this spring
summered over
now exploding in production

jalopeno peppers and poblano peppers
summered over also

egg plant planted this spring
summered over now bursting with production

okra lots of okra
clemson spineless and red german okras

malibar spinach that grows on a vine
the hotter the weather the better it likes it
providing spinach for salads casseroles grilling
all summer and fall

garlic from the spring harvest
some i just replanted this last week
to be harvested next april

rosemary plucked from the plant by our front door

green and red tomatoes
from a juliet tomato that just popped up
when i planted my citrus tree this spring
that nature shes good
this plant has provided us months of fresh tomatoes

the country n
the farm to fork place

the organicgreen doctor

Wednesday, October 19, 2016

alzheimers news- much adu


i am hoping that the following is a
game changer
for myself my siblings
all those infected with alzheimers disease
for all those who will be infected with alzheimers

if you have not read my recent blog titled its time
then consider reading it first before preceding further

the amyloid theory for alzheimers is that beta amyloid
accumulation in the brain causes alzheimers disease
if you remove the beta amyloid
alzheimers is controlled or if we are lucky cured

now enter 2016
there are now drugs that do this are being studied right now
to see if they work

if they do
they could be approved by the fda in 2-3 years
maybe sooner

since i have mild cognitive impairment amnestic type
the precursor to alzheimers disease
i may be a good candidate for this drug

in theory
if i take one of these drugs
if it works
my disease will be stopped in its tracks
maybe prevented
maybe controlled

in the next 5 years we will know if this stuff really
does what it suppose to do

yesterday my wife she and i got up at 500 am
made the 3.5 hour drive to
the alzheimers disease center at the
university of texas southwestern medical school
do my annual evaluation there
to get more information about a new treatment study
on patients with my diagnosis
mild cognitive impairments amnestic type
those with positive amyvid pet scans showing the bad
bad beta amyloid in the brain
the hallmark of alzheimers disease

we met with the head of the department there
with the research director who is running this new study

this new drug is called aducanumab
for short i call it the adu drug

this is what i called an alzheimers vaccine
it is an antibody that will be given as a monthly infusion
lasting an hour for maybe up to 180 weeks

in theory it goes into the brain removing the beta amyloid
from the brain and spinal fluid
if this works two things would be noticed

the amount of beta amyloid in the brain gets decreased
so you can see on the amyvid pet scan the marked decrease

a persons memory gets better or stays the same
it doesnt worsen
im hoping for the gets better version

in phase 1 studies of the adu drug
thats what happened
the amyvid scans got better
folks memory improved

so the company biogene skipped over phase 2 studies
directly to phase 3 studies

after 18 months if this stuff seems to work
the company will apply for fda approval

alzheimers drugs like some cancer drugs get fast track approval
by the fda
it could be available for the general population in 2-5 years

so what i just wrote is
there is a drug that may treat actually treat alzheimers disease

not like aricept which only treats symptoms not the disease
its probably one of the reasons i am better
but i know that effect will eventually end

that this new drug may be available in two years

so pay attention if you are at risk for this disease
it probably will be used eventually in folks
do not have symptoms yet
my siblings and relatives

at ut southwestern they will be signing up 20 people for this study
lucky for me is that i am the first person they will be signing up

i did some of the initial medical history stuff
got a neurological history and physical by the head of the department
got a memory test

like i told the examiner the memory test i hate the most
not the scans not the blood draws not the spinal taps not the infusions

i was given the 25 page consent form to review
i decided there is nothing in that form that will prevent me from doing this
it will take 33 trips to ut southwestern over 180 weeks to get this all done

i will do more medical history stuff
do more memory testing
they draw 240 ml thats about 50 tsps of blood
thats all submitted

if i pass those tests
then i do a mri maybe another spinal tap
my previous mris are normal
my previous spinal tap shows a decreased beta amyloid with low tau protein
the hall mark sign of alzheimers disease
the test that i have been waiting for
the amyvid pet scan that will show if i have beta amyloid in the brain

if its positive
they only take positive folks
i am in

plus i finally will know for as sure as one can that i have it
alzheimers disease

now i dont get to see the scan
if i enter the study that means the scan was positive

i do the monthly infusions for 18 months
getting more mris and blood tests and memory tests along the way

i will either be in the treatment group
the placebo group

at the end of 18 months
all placebo folks and all who got the real stuff
have the option to go another 100 weeks of treatment with

hopefully by the end
this stuff will be on the market

if accepted
if this works
i will get close to 4-5 years of treatment with an iv infusion
that hopefully will stop my alzheimers disease in its tracks
will regress it significantly

a real life changer for myself   my wife she   and my family

if it works i could see my granddaughter ms b
graduate from
middle school
high school
get married
have kids
i never thought i would be thinking

i realize this is not a guarantee
there may be side effects that show up that shuts this drug down
so far this one and others are not showing much of these side effects
except high doses of it might cause problems

as i read the potential side effects
you know you see them on your pharmacy prescription sheets
see them on tv at the end of the commercials
nothing in there scares me enough
i realize the side effect of not doing anything is much worse

ive seen it in my mom and my,younger brother
thats not the way i want to end all this

when this comes on the market it is expected to cost
close to $20,000 a year
if i get in the study i will get $100,000 of free drug
may get it free even longer if it gets continued

so here at the country n
my wife she and i are excited to be considered for this
ground breaking possibly historical drug study

smiles do abound around here today

its much adu about a lot

for more info on this study and contact information
go to this link for the alzheimers center ut southwestern
yes thats me and my wife she in that video

this link for the study being done in other states

here is an article on this drug

the organicgreen doctor