welcome to the organic green doctor blog

i am a family physician who was diagnosed with
early mild cognitive impairment(mci) amnestic type on december 21, 2010
this is a precursor to alzheimers disease
because of this diagnosis i have opted to stop practicing medicine
this blog will be about my journey with this disease
please feel free to follow me along this path
i will continue blogging on organic gardening, green living,
solar power, rainwater collection, and healthy living
i will blog on these plus other things noted to be interesting

Friday, June 23, 2017

alzheimers news-are these three the ones

ALZHEIMERS NEWS-ARE THESE THREE THE ONES
Image result for organicgreendoctor
i am waiting for the one
that will carry us to the promised land
that promised land of no more alzheimers disease

it might be within our reach now
if these three drugs pan out to work
to slow down or stop alzheimers

aducanumab

thats my drug
that i get monthly infusions of

its undergoing clinical studies now that will be completed in 2020
it works by
removing the bad beta amyloid from the brain
removing the plaques from the brain
stimulating microglial cells to clean up damaged areas in the brain

it showed much promise in phase one studies
it removed all the measurable amyloid plaques fron the brain in those studies
those folks also noted memory improvements

if this stuff works then this will be one way to treat folks with
the early symptoms of alzheimers disease or those with no
symptoms yet but who are in that prealzheimers state that can last
15-20 years before alzheimers symptoms start

bace inhibitors

these come in pill form
they block the formation of the beta amyloid in the first place
so there is none to be deposited in the brain
thus
alzheimers disease will be slowed or prevented
those studies are ongoing now in folks with mild symptoms
and those with no symptoms yet but who are in that prealzheimers state

eg
my brother would have started in that state in his late thirties
or early forties
i would have started in that state in my mid forties to early fifties

gamma secretase modulator (gsm)

this article describes who rudolph tanzi is
he is called the rock star of science
a well known alzheimers researcher
i have seen him on ted talks and on many of the alzheimers specials
that have been on tv

he and fellow researchers have developed this brain in a petri dish
that develops alzheimers disease
it the brain in a petri dish develops amyloid plaques then develops
tangles the hallmark those two of alzheimers disease

adding the gsm drug to this petri dish
makes the amyloid plaques go away or not form and there is no
formation of tangles

its the amyloid accumulation and the tangle accumulation that causes
brain cell death in alzheimers disease

the theory is
give this gsm pill to folks and none of this stuff will happen
no amyloid accumulation
no tangles
no alzheimers disease

studies will start on this drug in 2018 on humans
if it works in humans
its a huge discovery in helping in ending alzheimers disease

so
if these three things do work
we will know in about 3 or more years
then
i will get up each morning
take my bace inhibitor pill
then
take my gsm pill
then
once a month i will go to an infusion center to get my
infusion of aducanumab
and
if it really works all this stuff
i wont ever get alzheimers disease
which
i must add
i really fear like you of having that happen to me

remember
we need financial support to fight this disease
and
emotional support to deal with it

join us as we walk this year

we will be doing the
alzheimers texas walk in georgetown texas
on saturday september 23rd
team name is organicgreendoctor

i also will have a team in the
santa barbara walk to end alzheimers 
on saturday october 28th
team name is organicgreendoctor.com

join us

the organicgreen doctor

No comments:

Post a Comment