welcome to the organic green doctor blog

i am a family physician who was diagnosed with
early mild cognitive impairment(mci) amnestic type on december 21, 2010
this is a precursor to alzheimers disease
because of this diagnosis i have opted to stop practicing medicine
this blog will be about my journey with this disease
please feel free to follow me along this path
i will continue blogging on organic gardening, green living,
solar power, rainwater collection, and healthy living
i will blog on these plus other things noted to be interesting

Friday, April 13, 2018

alzheimers news-can they fix it


new atlas.com

we all have an apoe gene
its either apoe 2
its the lucky one is what i call it
it tends to protect you against alzheimers

it could be apoe 3
you may get alzheimers but it may be a mild case
whatever a mild case of alzheimers means

it could be apoe 4
apoe 4 is known as the late onset alzheimers gene
if you get one apoe 4 you risk increases over 5 x youll get alzheimers
if you get two of them your risk increases over 15-20 x

we all have two apoe genes
the possibilities are

apoe 2 apoe 2
apoe 3 apoe 2
apoe 4 apoe 2

apoe 3 apoe 3
apoe 3 apoe 4

apoe 4 apoe4

the best one is apoe 2 apoe 2

the worst one is apoe 4 apoe 4
less than 5% of us have this one

around 25% of you have the single gene apoe 4
apoe 4 apoe 2 or apoe 4 apoe3

here is a link to a recent research study where researchers
in the lab in growing human brain cells
were able to alter the apoe 4 protein so that it became
an apoe 3 protein which would carry with it the decreased
risk of getting alzheimers disease if it could be done in
human brains

they used a chemical on these brain cells programmed to make apoe 4
apoe 4 has a deformed protein that causes the bad beta amyloid
to accumulate in the brain cells causing them to die
the apoe 3 protein does not

this chemical changed the apoe 4 protein into an apoe 3 protein
since they differ only at one tiny location
this new apoe 3 protein works more normal in the brain

researchers are working to develop a chemical that could be
given to patients to change the apoe 4 protein to apoe 3 protein
which decreases remarkably the risk of developing
alzheimers disease

all i can say is
im game
they can give this new stuff to me when it comes along
i got first dibs

the organicgreen doctor

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