welcome to the organic green doctor blog

i am a family physician who was diagnosed with
early mild cognitive impairment(mci) amnestic type on december 21, 2010
this is a precursor to alzheimers disease
because of this diagnosis i have opted to stop practicing medicine
this blog will be about my journey with this disease
please feel free to follow me along this path
i will continue blogging on organic gardening, green living,
solar power, rainwater collection, and healthy living
i will blog on these plus other things noted to be interesting

Sunday, May 27, 2018

alzheimers news-whats next


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if you take a cholesterol drug
why do you take it

i know i know
because your doctor tells you to
why do you take it

you take the cholesterol drug so that down the road a few
years your arteries wont get all clogged up
and cause you to
have a stroke
have a heart attack

thats really why

so it is with the goal of a new alzheimers drug
you start it early years before its time to lose your memory

these new drugs
based on those in the works
prevents or removes beta amyloid from forming
prevents or removes the tau protein tangles that may form
after amyloid plaques form

both are believed to be what happens in alzheimers
to kill brain cells

all the new drugs for alzheimers slows or stops this process

they like the cholesterol drugs will really need to be started
before symptoms start to have their maximum effect

the problem is many of them may not work at all
either they were tested wrong or they just dont work

some may have been tested in folks way too advanced in the
disease to have an affect on the outcome

much like taking cholesterol drugs after youve had
a major heart attack or stroke
it may help some but not much

we are now at the point
maybe a breaking point
in alzheimers research where its possible none of these new drugs
will work to cure or treat alzheimers

a former patient was diagnosed with lymphoma
she is about to start a 5 drug regimen to treat her lymphoma
which is now considered a curable cancer

one of the drugs she will take is an antibody against a protein
on the lymphoma cancer cell
it grabs the protein by doing so kills the lymphoma cell

my drug aducanumab grabs the beta amyloid protein and
extracts it from the brain

they work similar ways but on different proteins

now her antibody will not totally wipe out the lymphoma
thus she will be given 4 other drugs that each attacks the
lympoma cancer in different ways
they will weaken the cancer so it gets wiped out completely
ie a cure

thats what i think will happen in alzheimers treatment
my drug eg will be given to remove and prevent more amyloid
from being formed
being developed are drugs that attack the alzheimers forming
mechanism in the brain in different ways
this combo like the lymphoma treatment
may cure or keep the alzheimers at bay or stop it where its at

i read an article just this week that aricept (donepezil) that i take
that if given to prealzheimers folks
those who have beta amyloid accumulation with no symptoms
this may delay the deposition of beta amyloid if the aricept is
started early

oh wait what if you took aducanumab my drug with the aricept
would that make it work better like with treating cancer

i hope so since im on both of those now

usually aricept is started when symptoms start and the disease
starts to worsen

this week i noticed that he company that makes my drug has
gotten a favorite recommendation from the financial world
because well it seems the financial world seems to know these
things before the scientific world gets the information out
to all of us

i think what will happen is
aducanumab will not cure alzhiemers
it may slow it down or stop it where its at but if its stopped
the alzheimers will then take off again

a combo regimen will have to be used

well at least i am like my former patient with lymphoma
i am getting the preliminary treatment with my antibody to clear
things out until that regimen is invented

please hurry
we can hold down the fort for only so long

the organicgreen doctor

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