welcome to the organic green doctor blog

i am a family physician who was diagnosed with
early mild cognitive impairment(mci) amnestic type on december 21, 2010
this is a precursor to alzheimers disease
because of this diagnosis i have opted to stop practicing medicine
this blog will be about my journey with this disease
please feel free to follow me along this path
i will continue blogging on organic gardening, green living,
solar power, rainwater collection, and healthy living
i will blog on these plus other things noted to be interesting

Wednesday, December 14, 2022

my story revisited #162-more on supplements


when i wrote this old blog below i was taking a lot of supplements based on research articles that i had read that suggested that they might help but werent definitely scientifically proven to work

i also was taking a vitamin b complex giving me extra amounts of vitamin bs that i might need

after i got sick 2 years ago i couldnt tolerate the b complex anymore since they worsened my indigestion
thats also when i started weaning off some of my supplements 
i chose the ones that werent proven science and werent based on abnormal labs

vitamin d vitamin b12 folic acid i take based on abnormal labs described in the blog below

one supplemnet i was taking was resveratrol 
its found in red wine and other grape fluids peanuts blueberries and dark chocolate 

a large study was being done at that time that was looking to show if it really helped slow down alzheimers
so i started taking it
later i discontinued it when the study showed it may not help any
later another study said it might help
i stopped it

i was drinking red wine each day but after i was sick two years ago i couldnt tolerate it anymore
ive not had any red wine or alcohol for over two years
bummer i say
i loved a glass of red wine premeal each night

what we know is science ebbs and flows
what might work today turns out later it doesnt

it is nice not to swallow all of those supplements every day
now i only take vitamin b12 folic acid vitamin d3

remember if you take any supplement or vitamin check with your providers and also check on the webmd  drug interaction site to see if they interfere with each other and or your prescription or over the counter medications

it would take me about 3 more years to start stopping some of my supplements
the covid illness finish my supplement use except for those 3 listed above plus my probiotic


thats a misspelling i made up for the chemical
its a hope that i have and that researchers have
that reverse is what it can do

more in a minute

a correction to last fridays blog
i wrote the results of the ucla study was not anecdotal
the author when i went back to review it says clearly
these results are anecdotal
i guess when a more lengthy study involving more people
with a control group is done then this can be considered
not anecdotal

as i said last week
time is not on my side
i cant wait for that to happen

i got all my labs back
my crp was normal
8 years ago it was elevated
its a measure of inflammation
i still plan to continue the vit e omega fish oil curcumin and
good dental hygiene


my homocysteine level is elevated
8 years ago it was up and now its higher
this time its is 13.7 with the recommended level <7

it is an amino acid that has been shown if it is elevated
a person may have a doubled chance of getting alzheimers disease
the treatment which i will do is to take folic acid at 0.8 mg a day
the dose a pregnant lady takes in her prenatal vitamins
and will also take b12 and vit b6 also which may help decrease
the homocysteine level

my vit b12 level was slightly low at 162 with the normal level
being >192
for this result i was surprised
i dont eat a lot of  meat
i do eat an egg a day
i do eat cheese twice a day
i dont eat fortified cereals
i rarely ever eat seafood
or fish
i think my low level may be due to the chronic reflux i have
and the fact i take acid reducers every day
i will start taking a vit b12 supplement level every day to bring
the level back up to normal
i will take 1mgm or 1000mcg a day
a low b12 level can be a cause of memory loss
although my level is probably not low enough to cause memory loss
but it could have eventually got there

my 25-oh vit d3 level was slightly low at 46
recommended levels are 50-100
this one i was surprised at since i get so much sunlight
i frequently use sunscreen but will leave it off some
so i can get sunlight directly on my skin
if you saw my farmers tan you would believe me
i dont ever drink milk but do eat cheese twice a day
i will add 25-oh vit d3 at a dose of 500-1000 units a day

my thyroid levels and testosterone levels are normal

i will repeat these levels on the above tests in 6 months to
ensure they are back to normal
and will probably have to stay on the supplements long term

now back to reverse a trol

resveratrol is a chemical that is found in grapes peanuts blueberries
and dark chocolate
it is thought to reverse the srti ratio in the brain which means it
increases the production of an anti aging enzyme

a 12 month study done at multiple sites in the us will be published
this year
patients were given high doses of reverse a trol (sic) and levels
of the bad stuff beta amyloid and tau protein were measured
as well as neuropsych tests were done
anecdotally theres that word again some people reported an
improvement in their memory during the course of the study

for me this supplement may be important as people like
me who have the apoe4 gene have a reversal of the srti ratio
which means we dont make enough anti aging enzyme
by taking the reverse a trol (sic) the ratio will be increased
and the disease process may slow down

heres another supplement ill add to my regimen today

resveratrol starting at 500 mg then ill probably max it out
at 2000 mg if i tolerate it ok
i will adjust the dose some when the study results are published

so now im all ready for my regimen of
16 supplements
if you are in the alzheimers world or about to enter that world keep a close eye on lecanemab
as i hear all these national neurology and alzheimers experts i read and hear excitement over this drug
the same was noted when i was in for my last infusion last week at ucla

yes a lot of excitement
most feel this drug will be approved by the fda next year and probably medicare will agree pay for it
it will be used only in folks like me who are early in the disease

i plan on finishing my study which will take over 2 more years
then i will decide whether to take my drug aduhelm or lecanemab long term after my study is finished

stay tuned
we need some good news

lets see what ill be writing about all this in my blog 8 years from now
if i am still writing my blog then
you will know these medicines worked

the organicgreen doctor

follow me on twitter
follow my blog facebook page

No comments:

Post a Comment