welcome to the organic green doctor blog

i am a family physician who was diagnosed with
early mild cognitive impairment(mci) amnestic type on december 21, 2010
this is a precursor to alzheimers disease
because of this diagnosis i have opted to stop practicing medicine
this blog will be about my journey with this disease
please feel free to follow me along this path
i will continue blogging on organic gardening, green living,
solar power, rainwater collection, and healthy living
i will blog on these plus other things noted to be interesting

Friday, October 6, 2017

alzheimers news-#8 done and more

Image result for organicgreendoctor
we got this now
is what i told my wife she as we were zooming down the 101
turning onto that notorious 405
we are about to enter the mouth of the beast
i told her
i was talking about the traffic not the study i am in

its a 1.5 to 3 hour drive one way to ucla from where we live
how long it takes is based on the traffic and the time of day
i must say for our 800 am appointment we just zoomed right there

when we were going to ut southwestern in dallas for my
aducanumab study to get my infusions
it was usually a 3-3.5 hour drive
we dont really complain about the la traffic
well we do but we shouldnt since we get to la quicker
than we did to dallas

so this aducanumab im getting as an infusion is made by biogen
it removes the bad beta amyloid that starts the
alzheimers cascade of events that leads to the brain cell
destruction that causes the symptoms and signs
that you see in your loved ones

the theory is removing the beta amyloid may make a

it seems from what i read this morning that wall street
likes biogens chances of producing a drug that will
alter alzheimers disease
its interesting that sometimes wall street knows things
we dont know

then this morning i read about dr tanzi from harvard talk
about his research on being able to grow a minibrain
in a petri dish that did what they predicted

first beta amyloid was produced
then brain cells died
plaques fomed
then tau proteins unraveled
then inflammation occurred
then the minibrain started dying

this is what the theory of amyloid causing alzheimers says
it just got proven in a petri dish

if this aducanumab stuff works like it did in the early studies
the phase 1 study
it removed all of the beta amyoid after a year in all of those in the
early study who had received the aducanumab
the placebo folks had no change maybe just it got worse

so if this stuff aducanumab really works
i and others will get better

as least wall street the stock market thinks it might work

the first results of our study should be out in 2019 or 2020
by then i will have gotten if i got the real stuff which i think
i am getting
at least 3 years of the drug before the results come out

in alzheimers years 3 years is a long long time

another article i read which sort of sucks is that the fda may
make them use it in folks who already have symptoms
who may not be helped as much by this new drug
to really be effective like a lot of the new drugs have to be given
to folks who do not have symptoms yet or who like me have minimal
so that this amyloid stuff doesnt accumulate in the brain
even i may be too late too far along to get the maximum benefect
from this drug

i want to be the first person to proudly hold up this flower
at the alzheimers walks in the future


its the flower thats reserved for the first alzheimers survivor

support us at our next walk
donate and or walk at your local walk

santa barbara walk to end alzheimers october 28th

the organicgreen doctor

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