welcome to the organic green doctor blog

i am a family physician who was diagnosed with
early mild cognitive impairment(mci) amnestic type on december 21, 2010
this is a precursor to alzheimers disease
because of this diagnosis i have opted to stop practicing medicine
this blog will be about my journey with this disease
please feel free to follow me along this path
i will continue blogging on organic gardening, green living,
solar power, rainwater collection, and healthy living
i will blog on these plus other things noted to be interesting

Friday, October 30, 2020

alzheimers news-its getting closer to approval


biogens aducanumab drug for alzheimers disease goes before the fda advisory committee next week on friday november 2020
here is the link to information on the meeting

if it is approved it could be available for use to slow down alzheimers disease as early as march 2021
the fda may make biogen do another extension of the trial that i am in 
they may make them do a lengthy phase 4 study that will delay its approval for several years

i got a notice this week that the alzheimers association sent this letter supporting aducanumabs approval for use in alzheimers disease

the aducanumab is an antibody against amyloid
it was discovered in elderly folks who dont get alzheimers disease
the drug company makes it in the lab in large quantities 
when given intravenous it removes the amyloid from the brain

in the phase 3 study that i am in it did remove amyloid from the brain such that a year after receiving it those on the higher dose had most of the amyloid removed from the brain
they also had the tau protein another culprit in alzheimers disease reduced in number
they also noted that folks activity of daily living and their memory decline got better taking the drug

i got 18 month of the placebo then i got 7 months of a high dose of aducanumab before the study was halted
i suspect if i had an amyvid pet scan done it would show that the amount of amyloid in my brain would have declined

i should find out in two weeks when this study i am in will be reactivated
if it is reactivated then i will receive the infusions for about 2 years more
if it is not reactivated then i plan on starting the infusions whenever the fda approves it for general use

it has been since 1996 since aricept was approved for use in alzheimers disease
now 14 years later we may have biogen aducanumab approved for use in alzheimers disease

im ready to restart the drug aducanumab whichever way i can get it

the studies to get the drug in research studies are closed

there is a drug called ban2401 that is in phase 3 studies ongoing now
here is the link on clinicaltrials.gov that  tells you more about that drug
it works similar to my drug aducanumab and is also made by biogen

i am excited to hear what the fda committee says about aducanumab
real excited

become involved with the alzheimers walks in your area
they are all being done virtually this year
find one and participate
you will make good contacts with folks that can help you when the time comes

here below is the information on my team organicgreendoctor that will walk in this years santa barbara walk to end alzheimers on saturday november 7 2020
the opening ceremony will be virtual
so anyone can watch it online
each individual member will walk in their neighborhood or favorite hiking trail wearing their purple alzheimers shirts for the 2-3 mile walk 
this is the safest way to do the walk this year
please wear your mask and keep a good social distance from others
hopefully next year we can all be live

here is the link to our team
the organicgreendoctor team

donate and or join us that day
you can walk wherever you live

maybe 2021 will be a good year

the organicgreen doctor

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