welcome to the organic green doctor blog

i am a family physician who was diagnosed with
early mild cognitive impairment(mci) amnestic type on december 21, 2010
this is a precursor to alzheimers disease
because of this diagnosis i have opted to stop practicing medicine
this blog will be about my journey with this disease
please feel free to follow me along this path
i will continue blogging on organic gardening, green living,
solar power, rainwater collection, and healthy living
i will blog on these plus other things noted to be interesting

Friday, May 14, 2021

alzheimers news-we are anxiously waiting for june 7th


what is so special about june 7th
its a big deal in the alzheimers world
its the day that biogens aducanumab gets voted on for fda approval

if its denied 
a lot of hope get lost for awhile
for some of us 
were done 
there will not be another option probably for us

aducanumab is an antibody against amyloid that was produced after it was isolated from older folks who seemed to not get alzheimers

the aducanumab is made in the lab and is given as monthly infusions
its discovered that the dose of aducanumab is 10 mgm

that dose was discovered to be the best one to work near the end of a recent alzheimers study

the fda advisory committee voted not to recommend approval of aducanumab in alzheimers disease
the full fda panel has the final say so on june 7th

the alzheimers association however is a big supporter of having it approved for use in alzheimers

almost 8 years ago i found research articles about aducanumab
i after several months of being evaluated for possible acceptance into the biogen aducanumab study 
was finally accepted to receive monthly infusions for about 25 months
i as it turned out got 18 months of placebo 
that sucked
i did get 7 months of the real drug
which means i got a tapering dose that increased each month until i got the full 10 mg dose
i dont know how many doses i got of the 10 mg dose

they taper it up since this drug causes microbleeds that can show up on mris called arias
my mris dont show this has happened
this is the major side effect of taking the drug
these microbleeds tend to resolve
no one has been injured from taking the drug

even if i had a small stroke from taking the drug im ok with that happening
i would be ok if that happened after taking something that might slow things down 

i am now being evaluated for restarting my aducanumab infusions
i have to do a amyloid pet scan called amyvid and a tau pet scan first
i hope to get approved for getting 24 months of infusions of aducanumab
if its not approved by the fda then i will still get at around 24 infusions
if its approved by the fda then ill just keep taking it after the 24 months research study is done

even if i just get 24 months of the infusions  it  might have slow things down for awhile 
awhile i will take any time

here is a bloomberg article i read this morning on the aducanumab fda approval decision on june 7th
there is a story in the article of an alzheimers patient more advanced than me that feels the aducanumab has slowed down the disease

my vote if i was on the fda panel would be
to vote its approval
22% improvement is worth it to those of us with this diagnosis
we will take 22% every time

fingers crossed

the ogainicgreen doctor

No comments:

Post a Comment