welcome to the organic green doctor blog

i am a family physician who was diagnosed with
early mild cognitive impairment(mci) amnestic type on december 21, 2010
this is a precursor to alzheimers disease
because of this diagnosis i have opted to stop practicing medicine
this blog will be about my journey with this disease
please feel free to follow me along this path
i will continue blogging on organic gardening, green living,
solar power, rainwater collection, and healthy living
i will blog on these plus other things noted to be interesting

Saturday, May 14, 2022

alzheimers news-will this be the next one approved to treat alzheimers


this will probably be the next drug used to treat alzheimers disease
will it cure alzheimers disease
it will probably slow it down some probably better than my drug aduhelm or aducanumab

lecanemab is made by eisai and they and biogen who makes my drug are doing the research on it and will be marketing it 
hopefully better than aduhelm or aducanumab was 

lecanemab is a monoclonal antibody given by infusions either bimonthly or monthly
it binds to the protofibrils of the amyloid in the brain
in clinical trials it removes all measurable amyloid in the brain after 18 months

it seems to show like aduhelm or aducanumab there is slowing of cognitive decline 

it is in the final parts of its phase 3 clinical trials
eisai will apply for approval for its use in mci and early alzheimers disease later this year

hopefully it will do a much better job of applying to the fda for approval than biogen did with aduhelm

it probably will work better than my drug aduhelm

the question will be will the fda approve it and will medicare pay for it

in searching clinicaltrials.gov for ongoing studies that was using lecanemab and taking new study subjects i found only two

one was on preclinical or prealzheimers or prodromal alzheimers patients
these patients have no symptoms but have measurable amyloid in the brain
that would have been me at 55
my amyloid scan or blood test would have been positive for amyloid

the other was on the dominant inherited early alzheimers patients
these folks have a gene for early onset alzheimers

here is the link on clinicaltrials.gov for these studies

there are a lot of folks out there who qualify for these studies

i am sure there will be more studies using lecanemab in mci and early alzheimers that come along later

my guess this one works better than my drug aduhelm or aducanumab

interesting is they are using one of the new blood tests for alzheimers disease to screen folks for these studies

these similar blood tests will be available eventually in our primary care offices for those patients who want to know if they have alzheimers disease

no i dont want to know
wrong i say 
find out 
then do something about it
before its too late

it will be like not wanting to know you have bad cholesterol levels
you want to wait until you have a heart attack or stroke or alzheimers disease to do something about it
then its too late to help much

the organicgreen doctor

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