welcome to the organic green doctor blog

i am a family physician who was diagnosed with
early mild cognitive impairment(mci) amnestic type on december 21, 2010
this is a precursor to alzheimers disease
because of this diagnosis i have opted to stop practicing medicine
this blog will be about my journey with this disease
please feel free to follow me along this path
i will continue blogging on organic gardening, green living,
solar power, rainwater collection, and healthy living
i will blog on these plus other things noted to be interesting

Friday, November 18, 2022

alzheimers news-what does chris hemsworths labs mean


folks are always asking me questions about alzheimers disease
yesterday a lady asked me about her two relatives
one she said had early onset alzheimers disease
he was in his mid 70s and was on aricept or donepezil

early onset alzheimers is a genetic disease that represents around 1% of all the cases of alzheimers disease
if you get the gene you are going to get the disease 
the symptoms start usually in the 40s or 50s
folks with the disease die in their 50s or early 60s

i think she meant he had early or mild alzheimers disease
very few if any early onset alzheimers disease patients are alive in their mid 70s

then there is the late onset alzheimers disease gene
late onset alzheimers occurs in the mid 60s and beyond
its associated with the late onset alzheimers gene called apoe 4
if you get one version your risk is increased by about 5 times
if you get two versions apoe 4 apoe 4 then your risk is increased about 20 times

it doesnt mean you will get alzheimers disease but you are at increased risk

if you are vigilant and control your blood pressure your cholesterol your diabetes control you anxiety and depression get adequate sleep dont smoke control you weight stay active physically mentally and socially avoid excessive alcohol use dont smoke you might be able to prevent or slow down the risk of getting alzheimers disease

this lady had another elderly relative who has alzheimers disease
he is on aricept or donepezil and is also doing well
he probably has the apoe 4 gene 

then i saw this article linked here on chris hemsworth
who is he i thought
so i googled him
i know i know some of your females know who he is
he is thor
he is doing a series for disney plus national geographic doucseries called limitless
you can read the article or watch the trailer to find out all the dangerous things he does in that series

here is the link to the trailer for the docuseries limitless
one dangerous thing he did was do his genetic testing for alzheimers disease
the results was read to him live on his limitless program
note im not sure if its aired yet on disney plus

i am looking forward to seeing that program to see how he reacts and how they explain what his labs all mean

my advice to thor
since you are 39 years old you have time left to counterbalance the fact you have the double version or homozygous apoe 4 apoe 4 late onset alzheimers gene

just do those things that are listed above
watch the alzheimers clinical trials closely
keep your eye on the drug studies that start treating folks who are prealzheimers or prodromal alzheimers

prealzheimers or prodromal means you have changes in the brain for amyloid and tau that can be detected soon with blood tests but now with spinal taps for amyloid and tau and now with amyloid pet scans and tau pet scans
but you dont have symptoms 

sorry to tell you its possible that in 10 years if you are going to get alzheimers those blood tests and spinal fluid tests and pet scans will be positive

thats when you will be called prealzheimers if you are having no symptoms
you want to get in a clinical trial with a drug that will remove the amyloid and maybe the tau tangles before they can do too much damage
its also possible that by 10 years those drugs will probably be available outside clinical trials

it will be like keeping you cholesterol levels in the normal range so you wont get a heart attack or stroke later in life

i dont think i would test your younger kids though
let them make that decision themselves later in life

i did notice though that he is doing some real dangerous filming for his docuseries called limitless
if he is not careful he wont have to worry about having the apoe 4 gene

for the rest of you i wouldnt get the apoe 4 gene testing unless you understand what it all means
im sure and i look forward to watching the show where he is told the results
hopefully they did some genetic counselling before hand

there is a nice paragraph in the article i linked where he says
“Most of us, we like to avoid speaking about death,” he explained. “Then to all of a sudden be told some big indicators are actually pointing to this as the route which is going to happen, the reality of it sinks in. Your own mortality.”

i know when i did my memory testing 12 years ago i remember the overwhelming sinking feeling i felt when i couldnt remember things 
i had that same feeling again when i got my positive apoe 4 apoe 4 results
i again had that same feeling when i got my positive spinal fluid results
i really had that same feeling maybe worse when i got my positive amyloid pet scan results
its the one that verified
man you definitely have it

my approach has been his approach he described in the article

dont do it if you dont think you can deal with it

the organicgreen doctor

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