welcome to the organic green doctor blog

i am a family physician who was diagnosed with
early mild cognitive impairment(mci) amnestic type on december 21, 2010
this is a precursor to alzheimers disease
because of this diagnosis i have opted to stop practicing medicine
this blog will be about my journey with this disease
please feel free to follow me along this path
i will continue blogging on organic gardening, green living,
solar power, rainwater collection, and healthy living
i will blog on these plus other things noted to be interesting

Friday, June 11, 2021

alzheimers news-here we go again


this is me standing outside the ucla building that houses the pet scanner where i had my amyvid pet scan for amyloid yesterday
this is the scan that will show how much amyloid i have left up in my brain
some of it was removed thats the amyloid not the brain when i did those 7 months of infusions of aduhelm (aducanumab) before the biogen aducanumab study was halted
how much was removed and has remained gone will show up on this scan
that will be my new starting point when i restart my infusions of aduhelm (aducanumab)

amyloid accumulates in the brain over years and is the first part of the alzheimers disease process followed then by tau protein accumulation then followed by inflammation

aduhelm (aducanumab) attacks just the amyloid and over time removes most of that that can be seen on an amyvid or amyloid pet scan

so yesterday i got my new baseline amyvid pet scan

heres how its done

they start an iv on you

then they inject you with this radioactive material that binds to the amyloid in the brain
you have to wait about 30-50 minutes after the injection before the scan is done

they then put you in this pet scanner 
its much quieter than a mri and is less confining
the scan takes about 25 minutes
then you are done 

if the scan is negative it will look like the one on the left
if its is positive it will look like the one on the right

my guess if some of my amyloid was removed and not replaced since my last infusion that my amyvid pet scan will look halfway between the two 
the scan may show some clearing of some of the amyloid

alas i will never see the scan or be given the results

im ok with that
my goal is to get my infusions of aduhelm (aducanumab)

in 3 weeks i go back to get a tau protein pet scan in that same pet scanner except i will be injected with a radioactive material that this time binds to tau tangles in the brain
this tells the researchers how bad the alzheimers is 
it appears that aduhelm (aducanumab) may also remove some of the tau tangles

alas again i will not see those results

the moment we have been waiting for for over 2 years
in 1 week
i go back to ucla
i restart my monthly infusions of adhelm (aducanumab) for at least 24 weeks as part of a continuation of the biogens aducanumab study i was in  

i have followed the research and understand the controversy with this drug and i understand its limitations
like the others in the alzheimers world it gives us some hope

i must say we be stoked to get started

the organicgreen doctor

1 comment:

  1. Iam praying and pulling for you!! And the family that loves you! You won the lottery with family and friends, and may you win twice with the A ---- !!!