welcome to the organic green doctor blog

i am a family physician who was diagnosed with
early mild cognitive impairment(mci) amnestic type on december 21, 2010
this is a precursor to alzheimers disease
because of this diagnosis i have opted to stop practicing medicine
this blog will be about my journey with this disease
please feel free to follow me along this path
i will continue blogging on organic gardening, green living,
solar power, rainwater collection, and healthy living
i will blog on these plus other things noted to be interesting

Friday, September 17, 2021

alzheimers news-cholesterol and alzheimers disease


in listing all the healthy things one can do to help slow down or aid in the prevention of alzheimers disease along with things like controlling your blood pressure etc is controlling your cholesterol

when you get your lipid profile done
you get these numbers
total cholesterol
hdl cholesterol called the good cholesterol
ldl cholesterol called the bad cholesterol

usually you like to have the ldl cholesterol less than 100 when it comes to preventing heart disease and stroke and probably alzhiemers disease

as i have told folks 
if you are going to have to take cholesterol meds then get the ldl below 100

my original ldl cholesterol done when i was about 40 was well over 250
now after watching my diet and taking atorvastatin or lipitor it is less than 100

so i am helping to prevent heart disease and stroke and now probably alzheimers disease progression

what if i had really controlled my cholesterol like it is now for 71 years instead of just 30 years
would it make a difference


in this article from the university of virginia researchers say that cholesterol drives the formation of amyloid plaques

in alzheimers disease
amyloid plaques form first
then tau proteins unwind and form tangles
then neuroinflammation starts up
all three lead to brain cell death
alzheimers disease

they found that cholesterol produced in astrocytes in the brain use it to make amyloid plaques
these plaques deposited in the brain kill brain cells
thus starting the cascade of events that leads to alzheimers disease
ie amyloid plaques then tau tangles then neuroinflammation

these astrocytes cells make cholesterol then carry it to the brain cells or nerve cells or neurons where they are deposited
normally the amount of cholesterol deposited is kept low but in some cases too much cholesterol is deposited leaving amyloid plaques
thus killing brain cells

in mice studies they blocked this amyloid production by the astrocytes to slow down the production of the amyloid plaques

one treatment may be to used will be a medicine to block this overproduction of amyloid by the astrocytes to prevent the over deposition of the amyloid in the brain cells thus preventing amyloid plaque

in the meantime
ill keep following the research
ill keep my ldl cholesterol less than 100

remember whats good for the heart is good for the brain

the organicgreen doctor

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